NEO602 - ETHIOPATHOGENESIS and ADVANCED TREATMENT of SEVERE CIRCULATORY SYSTEM DISEASES of THE NEWBORN

Course Name Code Semester Theory
(hours/week)
Application
(hours/week)
Credit ECTS
ETHIOPATHOGENESIS and ADVANCED TREATMENT of SEVERE CIRCULATORY SYSTEM DISEASES of THE NEWBORN NEO602 2nd Semester 2 2 3 7
PrequisitesLimited to a quota of 10 students.
Course languageTurkish
Course typeMust 
Mode of DeliveryFace-to-Face 
Learning and teaching strategiesLecture
Discussion
Question and Answer
Observation
Drill and Practice
Problem Solving
 
Instructor (s)Murat Yurdakök, Åžule YiÄŸit, H. Tolga Çelik 
Course objectiveThe aim of the course is; cardiotonic drugs, circulatory system diseases (congenital heart diseases, patent ductus arteriosus, arrhythmias, pulmonary hypertension) diagnosis, treatment, management and to provide up-to-date knowledge and experience about ECMO treatment. 
Learning outcomes
  1. Hemodynamic evaluation and follow-up of newborns
  2. Cardiotonic drugs
  3. Circulatory system diseases
  4. Patent ductus arteriosus
  5. Arrhythmias
  6. Pulmonary hypertension
  7. ECMO treatment
Course ContentLearning hemodynamic evaluation and follow-up of newborns, cardiotonic drugs, circulatory system diseases (congenital heart diseases, patent ductus arteriosus, arrhythmias, pulmonary hypertension) diagnosis, treatment, management and ECMO treatment. 
ReferencesFanoroff and Martin?s Neonatal-Perinatal Medicine, 11thEdition, Martin RR, Fanaroff AA, Walsh MC. 2020. Elsevier ISBN:9780323567114.
Avery?s Diseases of the Newborn, 10th Edition, Gleason CA, Juul SE, Elsevier 2018, ISBN: 9780323401395.
Fetal and Neonatal Physiology, 5th Edition, Polin RA, Abman SH, Rowitch DH, Benitz WE, Fox WW, Elsevier, Philadephia, 2017, ISBN:978-0-323-35214-7.
Visual Guide to Neonatal Cardiology, Alboralis ET, Hijazi ZM, Lopez L, Hagler DJ, 2018, Wiley Blackwell.
Yurdakök Pediatri (4 Cilt), Yurdakök M, Güneş Tıp Kitabevleri, Ankara, 2017, Cilt 1 ISBN:978-975-277-664-7, Cilt 2 ISBN: 978-975-277-665-4, Cilt 3 ISBN: 978-975-277-666-1, Cilt 4 ISBN: 978-975-277-663-0.
Prenatal Pediatri, Yurdakök M, Deren Ö, Yiğit Ş, Özyüncü Ö, Korkmaz A, Güneş Tıp Kitabevleri, Ankara, 2012, ISBN: 978-975-277-425-4.
Yenidoğan Bakımında Hacettepe Uygulamaları, Yurdakök M, Yiğit Ş, Çelik HT, Güneş Tıp Kitabevleri 2019, Ankara, ISBN: 978-975-277-753-8.
Literature related to the subjects will be given to students. 

Course outline weekly

WeeksTopics
Week 1Hemodynamic evaluation and follow-up of newborns -I (H. Tolga Çelik)
Week 2Hemodynamic evaluation and follow-up of newborns -II (H. Tolga Çelik)
Week 3Cardiotonic drugs (Murat Yurdakök)
Week 4Congenital heart diseases (Ä°lker ErtuÄŸrul)
Week 5Discussions - Case reports- Clinical practice
Week 6Midterm Exam
Week 7Patent ductus arteriosus -I (H. Tolga Çelik)
Week 8Patent ductus arteriosus -II (H. Tolga Çelik)
Week 9Arrhythmias (Ä°lker ErtuÄŸrul)
Week 10Discussions - Case reports- Clinical practice
Week 11Midterm Exam
Week 12Pulmonary hypertension (Åžule YiÄŸit)
Week 13ECMO - I (Åžule YiÄŸit)
Week 14ECMO - II (Åžule YiÄŸit)
Week 15Discussions - Case reports- Clinical practice
Week 16Final exam

Assesment methods

Course activitiesNumberPercentage
Attendance1620
Laboratory00
Application2110
Field activities00
Specific practical training00
Assignments00
Presentation00
Project00
Seminar00
Midterms220
Final exam150
Total100
Percentage of semester activities contributing grade succes2950
Percentage of final exam contributing grade succes150
Total100

WORKLOAD AND ECTS CALCULATION

Activities Number Duration (hour) Total Work Load
Course Duration (x14) 15 2 30
Laboratory 0 0 0
Application15230
Specific practical training000
Field activities000
Study Hours Out of Class (Preliminary work, reinforcement, ect)15460
Presentation / Seminar Preparation000
Project000
Homework assignment000
Midterms (Study duration)22040
Final Exam (Study duration) 12020
Total Workload4848180

Matrix Of The Course Learning Outcomes Versus Program Outcomes

D.9. Key Learning OutcomesContrubition level*
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1. Gaining up-to-date knowledge and experience regarding fetal and neonatal effects of high-risk pregnancies (maternal auto-immune, iso-immune and hypertensive diseases; teratogenic substance-drug or substance-alcohol use, non-immune hydrops fetalis, intrauterine-perinatal infections); problems about traumatic delivery and also diagnosis, treatment and management of these babies before, during and after delivery. X   
2. Gaining up-to-date knowledge and experience regarding development, maturation, surfactant metabolism of lungs, respiratory physiology in newborns, respiratory evaluation - follow-up, diagnostic approach to respiratory distress, ethiopathogenesis and advanced treatments of severe respiratory diseases of the newborn (respiratory distress syndrome, bronchopulmonary dysplasia, important congenital anomalies of the respiratory system), mechanical ventilation support in newborns X   
3. Gaining up-to-date knowledge and experience regarding hemodynamic evaluation and follow-up of newborns, cardiotonic drugs, diagnosis, ethiopathogenesis, management and advanced treatments of severe circulatory system diseases (congenital heart diseases, patent ductus arteriosus, arrhythmias, pulmonary hypertension), preoperative and postoperative care in congenital cardiac disaeses, ECMO treatment.    X
4. Gaining up-to-date knowledge and experience regarding prevention of central nervous system damage in newborns, central nervous system monitoring, ethiopathogenesis and advanced treatments of severe diseases of the central nervous system (perinatal hypoxic ischemic injury, hypoxic ischemic encephalopathy, bilirubin encephalopathy, kern icterus, intraventricular-intracranial hemorrhage, white matter injury, periventricular leukomalacia, congenital malformations of the central nervous system, neonatal convulsions, apnea), hypotonia, neuromuscular diseases, retinopathy of prematurity, diagnosis, treatment and management of pain in newborns, identification of newborns with neurological-developmental high-risk and their follow-up.  X  
5. Gaining up-to-date knowledge and experience regarding development of immune system in newborns, immunization of premature newborns, neonatal infections, sepsis, necrotizing enterocolitis, probiotic use in newborns. X   
6. Gaining up-to-date knowledge and experience regarding fluid, electrolyte, acid-base balance disorders in newborns, acute kidney injury, disorders of coagulation system (bleeding and thrombosis), hypoglycemia, hereditary metabolic diseases, disorders of calcium-phosphorus metabolism, diagnosis, treatment and management of osteopenia of prematurity  X  
7. Gaining up-to-date knowledge and experience regarding current, new and candidate treatment methods in neonatal diseases (mesenchymal stem cell, cellular-regenerative treatment methods), acute and enzyme / new drug treatments given to rare hereditary diseases (genetic, neurologic, metabolic etc) in neonatal period, renal replacement therapies, ECMO therapy, preoperative end postoperative care in newborn?s surgical diseases. Gains up-to-date knowledge and experience regarding medical and technical equipment used in the field of neonatology and uses computer and information technologies effectively.   X 
8. Learning ethical principles and problems related to perinatal-neonatal period and clinical research, ethics of scientific publications, legislation and legal regulations related to clinical research, their importance for the individual and society and to give genetic advice, obeys ethical principles. As an individual, behaves appropriately to laws, regulations and legislation regarding duty rights and responsibilities and also to professional code of ethics.    X 
9. Acquires theoretical and practical knowledge required by the field of neonatology, offers short- and long-term solutions to problems, obtains up-to-date and evidence-based scientific knowledge, follows current international literature, produces research hypothesis by combining it with scientific curiosity. Learns clinical and experimental scientific research planning; project writing, execution, finalization; scientific presentation methods; article writing methods; scientific article evaluation and basic concepts and skills related to research and publication statistics. Analyzes the results of the research with statistical methods, documents the evidence-based reports and presents them in national / international scientific fields.    X
10. Presentations, discussions and questions the themes related to neonatal diseases, and also his / her theoretical knowledge and opinions about applications independently or as a team manner in national and international scientific environments, defends the results within the framework of scientific evidence and ethical principles. Is sensitive and responsible for the problems related to health care and health policies concerning baby-child-mother-family and community health within the scope of Neonatology. Produces short- and long-term solutions to problems in individual and social context. Knows the importance of team work in the field of neonatology, works as a leader and / or team member, conducts research.     X

*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest