ADB735 - FORENSIC GENETIC ANALYSES and ESTIMATION

Course Name Code Semester Theory
(hours/week)
Application
(hours/week)
Credit ECTS
FORENSIC GENETIC ANALYSES and ESTIMATION ADB735 Any Semester/Year 3 0 3 8
Prequisites
Course languageTurkish
Course typeElective 
Mode of DeliveryFace-to-Face 
Learning and teaching strategiesLecture
Discussion
Question and Answer
 
Instructor (s)Assoc. Prof. Ergi Deniz ÖZSOY 
Course objectiveStatistical genetic analyses of Mendelian data are very important in the assessment of the suspect using DNA profiles and remains. In the first part of the forensic analyses and estimation methods course, basics of Mendelian genetics and its extension will be taught firstly. After that, population genetic theory will be shown with its extensions and instances relevant to human populations.  
Learning outcomes
  1. - Mendelian genetics and its extension; Mendelian genetics principals and extension of those principals to relax the model assumptions to cover the more realistic issues of genetics in general - Population genetic theory and its applications to human data.
Course ContentThe course content will folow the latest developments in genetic data thta can be Mendelized. Extensions of Mendelian genetics i.e. realisic dominance issues between alleles, genetic linkage and sex-linked inheritance, quantitative genetics, genetics of organelles. Population genetics theory that gives a sound general knowledge of classical selection, drift and molecular population genetics models. Mendelian genetics and population genetics aspects will complemet each other. 
References1. Introduction to Genetic Analysis. Anthony J. F. Griffiths, Susan R. Wessler, Sean B. Carroll and John Doebley. W.H.Freeman, 2010.
2. Elements of Evolutionary Genetics. Brian Charlesworth and Deborah Charlesworth.
Roberts and Company Publishers, 2010.
3. Genetics of Populations. P.W. Hedrick. Jones and Bartlett, 2009.
 

Course outline weekly

WeeksTopics
Week 1Basics of Mendelian genetics
Week 2Extension of Mendelian genetics 1
Week 3Extension of Mendelian genetics 2
Week 4Population genetics and genetic variation
Week 5Basic selection models 1
Week 6I. Midterm
Week 7Basic selection models 2
Week 8Relaxing the basic selection assumptions
Week 9Genetic drift
Week 10Inbreeding
Week 11Molecular population genetics 1
Week 12Molecular population genetics 2
Week 13Selection tests
Week 14Exercises
Week 15Preportion for final exam
Week 16Final exam

Assesment methods

Course activitiesNumberPercentage
Attendance00
Laboratory00
Application00
Field activities00
Specific practical training00
Assignments00
Presentation00
Project00
Seminar00
Midterms150
Final exam150
Total100
Percentage of semester activities contributing grade succes050
Percentage of final exam contributing grade succes050
Total100

WORKLOAD AND ECTS CALCULATION

Activities Number Duration (hour) Total Work Load
Course Duration (x14) 14 3 42
Laboratory 0 0 0
Application000
Specific practical training000
Field activities000
Study Hours Out of Class (Preliminary work, reinforcement, ect)1411154
Presentation / Seminar Preparation000
Project000
Homework assignment000
Midterms (Study duration)11515
Final Exam (Study duration) 12020
Total Workload3049231

Matrix Of The Course Learning Outcomes Versus Program Outcomes

D.9. Key Learning OutcomesContrubition level*
12345
1. Based on the graduate level proficiency improves and deepens the actual and advanced knowledge with original thought and/or research in the level of specialty.     X
2. Comprehends interdisciplinary interaction related with his/her field; performs analysis and synthesis of the new and complex ideas and reaches the original results by using expert knowledge in assessment.    X 
3. Evaluates and uses knowledge with systematic approach in his/her field; makes critical analysis, synthesis, and assessment of knowledge and transfer it.    X 
4. Develops a new idea, method, design and/or application for innovation in his/her field or performs a known idea, method, design and/or application to a different field. Researches an original subject; comprehends, designs, adapts and implements them   X  
5. Possesses the high level skills in using research methods in his/her field    X 
6. Publishes at least one article related with his/her field in national or international academic journals.   X 
7. Works in situation, which requires to solving original and interdisciplinary problems    X
8. Develops new ideas and methods related to his/her field using upper level intellectual processes such as innovative and critical thinking, solving problems and enacting.    X
9. Makes a scientific research at national or international academic groups    X
10. Contributes the solution of the social, scientific, cultural and ethical problems in his/her field and supports the improvement of these values   X 
11. Presents the scientific and technologic progresses in his/her field, contributes the processes of being an information society where he/she lives and continuation of this.   X 

*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest