MÄ°K744 - ANAEROBIC BACTERIOLOGY

Course Name Code Semester Theory
(hours/week)		 Application
(hours/week)		 Credit ECTS
ANAEROBIC BACTERIOLOGY MÄ°K744 2nd Semester 2 2 3 4
Prequisites
Course languageTurkish
Course typeElective 
Mode of DeliveryFace-to-Face 
Learning and teaching strategiesLecture
Discussion
Demonstration
 
Instructor (s)Assoc. Prof. Dr. GülÅŸen Hazırolan 
Course objectiveTo describe the oxygen requirement of bacteria and define the anaerobic bacteria, to explain the general properties of anaerobes, their role in normal flora, the virulence factors and the mechanisms of pathogenesis; the features and importance of anaerobic infections, diagnostic tests used in microbiology laboratories; microbiological properties of clinically important anaerobes as well as general principles of treatment and antibiotic resistance patterns  
Learning outcomes
  1. After completion this course the students are going to:
  2. 1. Classify bacteria based on their oxygen requirements, describe anaerobic bacteria
  3. 2. Explain the general properties of anaerobic bacteria
  4. 3. Get knowledge about the role of anaerobes in normal flora, virulence factors of these bacteria and the mechanisms of pathogenesis
  5. 4. Explains the clinical importance and charactheristics of anaerobic infections
  6. 5. Get knowledge about the anaerobic cultivation methods and other diagnostic tests used in microbiology laboratories
  7. 6. Get knowledge about the microbiological properties and clinical importance of medically important anaerobes
  8. 7. Explains the general principles of tretment and antibiotic resistance patterns of anaerobic bacteria
Course Content Classification of bacteria based on their oxygen susceptibilities, description of anaerobic bacteria; general properties and importance of anaerobes in normal flora; virulence factors and mechanisms of pathogenesis; clinical importance and charactheristics of anaerobic infections; diagnostic tests used in microbiology laboratories, microbiological properties of clinically important anaerobic bacteria; general principles of treatment and antibiotic resistance patterns of anaerobes  
References1. 1. Textbook of diagnostic microbiology. Connie R Mahon; Donald C Lehman (eds) 2019, 6th edition. St. Louis, Missouri : Elsevier.
2. Koneman?s Color Atlas and Textbook of Diagnostic Microbiology. Gary W Procop; Deirdre L Church; Geraldine S Hall; William M Janda; Elmer W Koneman; Paul Schreckenberger; Gail L Woods (eds) 2017; 7th edition, Philadelphia: Wolters Kluwer Health.
3. Enfeksiyon Hastalıkları ve Mikrobiyolojisi. Wilke Topçu A, Söyletir G, Doğanay M. 2017; 4. baskı , Nobel Tıp Kitabevleri; İstanbul
4. Medical Microbiology, 7th Edition, Patrick R. Murray, Ken S. Rosenthal, and Michael A. Pfaller. (eds) 2013; 7 th edition. Elsevier Health Sciences
5. Methods for Antimicrobial Susceptibility Testing of Anaerobic Bacteria. 9th ed. CLSI standard M11. Wayne, PA: Clinical and Laboratory Standards Institute. CLSI document M11-A7 (ISBN 1-56238-626-3).
6. https://www.eucast.org/clinical_breakpoints/Clinical breakpoints - bacteria (v 12.0) - file for printing (1 Jan, 2022). 

Course outline weekly

WeeksTopics
Week 1Bacteria and oxygen relationship; definitions
Week 2General properties of anaerobic bacteria
Week 3The role and importance of anaerobes in normal flora
Week 4Virulence factors of anaerobic bacteria and mechanisms of pathogenesis
Week 5General charactheristics and clinical importance of anaerobic infections
Week 6Group discussion
Week 7Microbiological diagnostic tests in anaerobic infections: Conventional methods
Week 8Microbiological diagnostic tests in anaerobic infections: semi automated and molecular methods
Week 9Demonstration: Anaerobic cultivation methods and media used in anaerobic microbiology
Week 10Anaerobic gram negative bacilli: clinical importance and microbiological properties
Week 11Anaerobic spore forming gram positive bacilli: clinical importance and microbiological properties
Week 12Anaerobic non-spore forming gram positive bacilli: clinical importance and microbiological properties
Week 13Anaerobic gram positive cocci: clinical importance and microbiological properties
Week 14General principles of treatment, antibiotic resistance of anaerobic bacteria
Week 15Preparedness for final exam
Week 16Final exam

Assesment methods

Course activitiesNumberPercentage
Attendance00
Laboratory00
Application00
Field activities00
Specific practical training00
Assignments00
Presentation220
Project00
Seminar00
Midterms00
Final exam180
Total100
Percentage of semester activities contributing grade succes120
Percentage of final exam contributing grade succes180
Total100

WORKLOAD AND ECTS CALCULATION

Activities Number Duration (hour) Total Work Load
Course Duration (x14) 14 2 28
Laboratory 0 0 0
Application14228
Specific practical training000
Field activities000
Study Hours Out of Class (Preliminary work, reinforcement, ect)14228
Presentation / Seminar Preparation21224
Project000
Homework assignment000
Midterms (Study duration)000
Final Exam (Study duration) 11212
Total Workload4530120

Matrix Of The Course Learning Outcomes Versus Program Outcomes

D.9. Key Learning OutcomesContrubition level*
12345
1. To acquire advanced, complete, evidence-based, current knowledge and skills in microbiology; follow the innovations in the field and gain the competence to propose innovations.   X 
2. To use evidence-based information for the planning of scientific research, research techniques and statistical analysis; to develop and carry out projects on demand and to publish/present the results.    X
3. To gain awareness, sensitivity and knowledge about the ethics of scientific work and legal regulations.    X
4. To be able to critically analyze and evaluate scientific research at an advanced level.   X 
5. To be able to present the information/data acquired via readings/research in front of a scientific community.    X
6. To use libraries, e-sources and e-journals subscribed by the department at adequate level.    X
7. To have knowledge about technological devices including computers, as required by the field of health.   X 
8. To use microbiology laboratories in accordance with good laboratory practices and biosafety rules and contributes to quality improvement.    X
9. To understand the purpose and interaction of different disciplines in the field and participate in solving complex problems.    X
10. To build relationships and share information regularly in professional environments (national/ international) and share their knowledge regularly.   X 
11. To participate in national and international projects and perform interdisciplinary studies.    X

*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest