DTE718 - DENTAL BIOLOGY
| Course Name | Code | Semester | Theory (hours/week) |
Application (hours/week) |
Credit | ECTS |
|---|---|---|---|---|---|---|
| DENTAL BIOLOGY | DTE718 | 1st Semester | 2 | 0 | 2 | 4 |
| Prequisites | For the students accepted to the PhD program | |||||
| Course language | Turkish | |||||
| Course type | Must | |||||
| Mode of Delivery | Face-to-Face | |||||
| Learning and teaching strategies | Lecture Discussion Question and Answer | |||||
| Instructor (s) | Prof. Dr. Arlin Kiremitci | |||||
| Course objective | To examine and analyse the formation ,development , organic and inorganic structure of dental tissues and oral biologic processes in an advanced level. | |||||
| Learning outcomes |
| |||||
| Course Content | 1. Tooth and its surroundings 2. Development of teeth and epithelium- ectomesenchyme interaction in tooth development 3. Development and structure of dentin 4. Development and structure of enamel 5. Development and structure of cementum 6. Chemical structure of teeth and trace elements 7. Nerve supply and sensitivity of teeth 8. Dentin regeneration 9. Dental stem cells 10. Tooth tissue engineering 11. Saliva | |||||
| References | Jansen van Rensburg, Oral Biology, Quintessence publishing, 2002,; Orban?s Oral Histology and Embriology , Mosby , 13th ed, , ; Tziafas D, Reparative Dentinogenesis,University Studio pres, 1997; Congle SHA, Regenerative endodontics, Dental clinics of North America, 2012, vol 56. | |||||
Course outline weekly
| Weeks | Topics |
|---|---|
| Week 1 | 1.1. Tooth and its surroundings 1.1.1 Tooth development and eruption 1.1.2 Components of a tooth 1.1.3 Periodontium 1.2 Development of teeth 1.2.1 Dental lamina 1.2.2.Dental papilla 1.2.3.Enamel organ 1.2.4 Dental follicle 1.2.5 The tooth germ |
| Week 2 | 2.1 Epithelium ?ektomesenchyme interaction in tooth development 2.1.1 The origin of ectomesenchyme 2.1.2 The mechanism of epithelium-ectomesenchyme interaction |
| Week 3 | 3.1 Development of dentin 3.1.1 Differentiation of odontoblasts 3.1.2 Formation of the matrix and mineralization |
| Week 4 | 3.2 Dentin 3.2.1 Chemical composition 3.2.2Odontoblasts and odontoblast processes 3.2.3. Predentine, incremental lines, amelodentinal junction, dentinocemental junction. |
| Week 5 | 4.1 Development of enamel 4.1.1 Determination of crown form 4.1.2 Differentiation of ameloblasts 4.1.3 Formation of matrix and mineralization 4.1.4 Maturation of enamel |
| Week 6 | 4.2. Enamel 4.2.1 Chemical composition 4.2.2.The structure of enamel, enamel crystals and rod sheaths 4.2.3 Lines of Retzius, Bands of Hunter-Schreger 4.2.4 Enamel defects |
| Week 7 | 5.1.Development of Cementum 5.1.1 Changes in the root sheath 5.1.2 Formation of cementum 5.1.3.Types of cementum |
| Week 8 | 5.2. Cementum 5.2.1 Chemical composition 5.2.2 Cementocytes 5.2.3 Sharpey?s fibers |
| Week 9 | 6.1 Composition of Teeth and trace elements 6.1.1Methods to obtain samples of tooth material 6.1.2 Chemical composition of teeth 6.1.3 Trace elements of teeth |
| Week 10 | 7.1.Nerve supply and sensitivity of teeth 7.1.1 Nerve supply to the dentine and pulp 7.1.2 Dental pain 7.1.3 Dentine hypersensitivity |
| Week 11 | 8.1 Dentin regeneration 8.1.1 odontoblast biology 8.1.2 pulp biology 8.1.3 pulp reperation, reactionary dentin, reperative dentin |
| Week 12 | 9.1. dental stemcells 9.1.1.dental pulp mesenchimal stem cells 9.1.2. 9.1.3 9.1.4 9.2 Tooth tissue engineering |
| Week 13 | 10.1 saliva 10.1.1. Physiology of saliva 10.1.2 biochemistry of saliva |
| Week 14 | Presentation |
| Week 15 | Final exam |
| Week 16 | Evaluation |
Assesment methods
| Course activities | Number | Percentage |
|---|---|---|
| Attendance | 0 | 0 |
| Laboratory | 0 | 0 |
| Application | 0 | 0 |
| Field activities | 0 | 0 |
| Specific practical training | 0 | 0 |
| Assignments | 4 | 10 |
| Presentation | 1 | 10 |
| Project | 1 | 20 |
| Seminar | 0 | 0 |
| Midterms | 1 | 10 |
| Final exam | 1 | 50 |
| Total | 100 | |
| Percentage of semester activities contributing grade succes | 4 | 50 |
| Percentage of final exam contributing grade succes | 1 | 50 |
| Total | 100 | |
WORKLOAD AND ECTS CALCULATION
| Activities | Number | Duration (hour) | Total Work Load |
|---|---|---|---|
| Course Duration (x14) | 14 | 2 | 28 |
| Laboratory | 0 | 0 | 0 |
| Application | 1 | 2 | 2 |
| Specific practical training | 0 | 0 | 0 |
| Field activities | 0 | 0 | 0 |
| Study Hours Out of Class (Preliminary work, reinforcement, ect) | 14 | 1 | 14 |
| Presentation / Seminar Preparation | 1 | 8 | 8 |
| Project | 1 | 20 | 20 |
| Homework assignment | 4 | 5 | 20 |
| Midterms (Study duration) | 1 | 6 | 6 |
| Final Exam (Study duration) | 1 | 12 | 12 |
| Total Workload | 37 | 56 | 110 |
Matrix Of The Course Learning Outcomes Versus Program Outcomes
| D.9. Key Learning Outcomes | Contrubition level* | ||||
|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | |
| 1. By utilizing and synthesizing the basic knowledge on dentistry and Restorative Dentistry, analyzes and resolves problems, achieves unique outcomes and novel treatment methods and educates the community about these developments. | X | ||||
| 2. Easily accesses to recent knowledge in Restorative Dentistry by utilizing fundamental master?s degree knowledge and by analyzing and synthesizing these knowledge, develops unique opinions. | X | ||||
| 3. Knows and effectively utilizes the technical equipment and instruments used for diagnosis and treatment purposes in preventive, conservative and restorative dentistry applications. | X | ||||
| 4. Shows awareness about ethical and legal responsibilities against his/her patients and the community. | X | ||||
| 5. Effectively communicates and establishes a dialogue with patients, relatives of patients and other health professionals. | X | ||||
| 6. Conducts a search for a scientific research on clinical and basic sciences, performs a literature search on a specific topic, conducts hypothesis, develops study plans, completes the research experiment, analyzes the data statistically and shares the data as minimally one scientific paper in national/international peer-reviewed journals or as a presentation in scientific meetings. | X | ||||
| 7. Internalizes and gets fully equipped about preventive dentistry applications such as oral hygiene motivation, individual caries risk assessment, diet analysis; and offers service to community. | X | ||||
| 8. By cooperating interdisciplinary health professionals, evaluates individualized treatment options for preventive, functional and esthetic needs; develops a patient/condition based treatment plan and applies the treatment. | X | ||||
| 9. Follows the recent advances on preventive, conservative and restorative dentistry treatments; offers clinical practice service to community with theoretical knowledge and practical skills gained. | X | ||||
| 10. Educates the patients and the community on etiologies and prevention of tooth hard tissue defects, motivates the patients for internalizing self-responsibilities. | X | ||||
| 11. Systematically analyzes and evaluates recent technologic developments and knowledge on preventive, conservative and restorative dentistry treatments and utilizes this knowledge on routine clinical practice. | X | ||||
| 12. Internalizes basic principles and knowledge on preventive, conservative and restorative dentistry treatments and combines this with recent evidence based information in professional practice. | X | ||||
| 13. Has a comprehensive knowledge on physical, mechanical, chemical and biocompatibility properties of restorative materials and assimilates the relationship between dental caries and microbiology | X | ||||
*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest