HÄ°S791 - THE INTERPRETATION of THE SUTRUCTURES UNDER ELECTR
| Course Name | Code | Semester | Theory (hours/week) |
Application (hours/week) |
Credit | ECTS |
|---|---|---|---|---|---|---|
| THE INTERPRETATION of THE SUTRUCTURES UNDER ELECTR | HÄ°S791 | Any Semester/Year | 1 | 2 | 2 | 5 |
| Prequisites | ||||||
| Course language | Turkish | |||||
| Course type | Elective | |||||
| Mode of Delivery | Face-to-Face | |||||
| Learning and teaching strategies | Lecture Discussion Other | |||||
| Instructor (s) | Prof. Sevda Müftüoğlu, MD, PhD., Prof. Petek Korkusuz, MD, PhD | |||||
| Course objective | To get the ability of evaluation and interpretation of ultrastructural features of cells and tissues in all organs | |||||
| Learning outcomes |
| |||||
| Course Content | 1. Examine and discuss the structural features of the cells and tissues of the organs under electron microscope. 2. Organelles including, nucleus, nucleolus are evaluated according to their ultrastructural criterias in connection with their functionalproperties 3. Cell differentiation, apoptosis or cell senescence and cell death are discussed in the light of EM features. | |||||
| References | 1. Glauert AM, Lewis PR. Biological Specimen Preparation for Transmission Electron Microscopy. 2. Maunsbach AB, Afzelius BA. Biomedical Electron Microscopy, 3. Dickerson GR. Diagnostic Electron Microscopy. 4. Fawcett D.W. The Cell 5. Matthews JL, Martin JH. Atlas of Human Histology and Ultrastructure 6. Porter KH, Bonneville MA, An Introduction to the Fine Structure of Cells and Tissues 7. Hayat MA, Principles and Techniques of Electron Microscopy Biological Applications | |||||
Course outline weekly
| Weeks | Topics |
|---|---|
| Week 1 | Examine cell membrane and nucleus |
| Week 2 | Define the organelles and inclusions |
| Week 3 | Define types of epithelial tissue and basal membrane |
| Week 4 | Examine the ultrastructural features of connective tissue proper with all of their components |
| Week 5 | Examine the ultrastructural features contractile cells and Describe the ultrastructure of nervous system; with all of their components |
| Week 6 | Midterm exam |
| Week 7 | Examine the ultrastructure of cardiovascular systems; with all of their components. |
| Week 8 | Examine the ultrastructure of respiratory systems; with all of their components. |
| Week 9 | Examine the ultrastructure of blood and lymphoid cells |
| Week 10 | Describe ultrastructure of digestive system with all of their components |
| Week 11 | Describe the ultrastructure of female and male reproductive system with all of their components. |
| Week 12 | Examine the ultrastructure of urinary system with all of their components |
| Week 13 | Examine ultrastructure of the endocrine system with all of their components |
| Week 14 | Artifacts, mistakes of fixation, embedding, sectioning and staining. |
| Week 15 | Preparation to final exam |
| Week 16 | Final exam |
Assesment methods
| Course activities | Number | Percentage |
|---|---|---|
| Attendance | 14 | 5 |
| Laboratory | 28 | 5 |
| Application | 0 | 0 |
| Field activities | 0 | 0 |
| Specific practical training | 0 | 0 |
| Assignments | 1 | 5 |
| Presentation | 1 | 5 |
| Project | 0 | 0 |
| Seminar | 0 | 0 |
| Midterms | 1 | 30 |
| Final exam | 1 | 50 |
| Total | 100 | |
| Percentage of semester activities contributing grade succes | 45 | 50 |
| Percentage of final exam contributing grade succes | 1 | 50 |
| Total | 100 | |
WORKLOAD AND ECTS CALCULATION
| Activities | Number | Duration (hour) | Total Work Load |
|---|---|---|---|
| Course Duration (x14) | 14 | 1 | 14 |
| Laboratory | 14 | 2 | 28 |
| Application | 0 | 0 | 0 |
| Specific practical training | 0 | 0 | 0 |
| Field activities | 0 | 0 | 0 |
| Study Hours Out of Class (Preliminary work, reinforcement, ect) | 14 | 4 | 56 |
| Presentation / Seminar Preparation | 1 | 6 | 6 |
| Project | 0 | 0 | 0 |
| Homework assignment | 1 | 6 | 6 |
| Midterms (Study duration) | 1 | 20 | 20 |
| Final Exam (Study duration) | 1 | 20 | 20 |
| Total Workload | 46 | 59 | 150 |
Matrix Of The Course Learning Outcomes Versus Program Outcomes
| D.9. Key Learning Outcomes | Contrubition level* | ||||
|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | |
| 1. Know the light and electron microscobic structure of the cells, tissues and organs; understanding the molecular and genetic components, establish the relationship between the structure function. | X | ||||
| 2. Understanding of the molecular mechanisms regulating human embryonic development , should be able to define the developmental disorders. | |||||
| 3. Know the basic techniques such as histochemistry, immunohistochemistry, electron microscopy, cell culture. | X | ||||
| 4. Must know and apply microscopic imaging techniques together and other quantitative methods such as stereology. | X | ||||
| 5. Must have the basic knowledge and competence necessary to perform laboratuary works such as IVF, stem cell technologies in cooperation with the clinics. | X | ||||
| 6. Must have knowledge, skills and attitudes that will contribute to education. | X | ||||
| 7. Should know how to obtain information to improve self and understand the importance of continuous learning. | |||||
| 8. Be able to put forward original hypotheses independently; plan and write original projects. | |||||
| 9. Have information and views on ethical issues on science and publication ethics and clinically related IVF and stem cell studies. | |||||
| 10. Be capable to participate in national and international scientific environments , make presentations and discussions. | X | ||||
| 11. Understand the evaluation criteria of the national and international journals and evaluate an article or project independently. | X | ||||
*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest