HÄ°S785 - THE DEVELOPMENT & HISTOLOGY of THE FACE & RESPIRAT

Course Name Code Semester Theory
(hours/week)
Application
(hours/week)
Credit ECTS
THE DEVELOPMENT & HISTOLOGY of THE FACE & RESPIRAT HÄ°S785 2nd Semester 2 0 2 5
Prequisites
Course languageTurkish
Course typeMust 
Mode of DeliveryFace-to-Face 
Learning and teaching strategiesLecture
Discussion
Question and Answer
Brain Storming
 
Instructor (s)Prof. Sevda MüftüoÄŸlu, MD, PhD, Prof. Petek Korkusuz, M.D, PhD 
Course objectiveEssential knowledge gain on the development of pharyngeal apparatus and related organs (tongue, salivary glands, thyroid), face, nasal cavity, palate, respiratory tract and organs under normal circumstances, possible developmental defects that emerge as anomalies/diseases, the histology of respiratory system and acquisition of the ability to recognize and define all respiratory system structures via the microscope 
Learning outcomes
  1. Acquisition of essential knowledge about the development of pharyngeal apparatus and related organs (tongue, salivary glands, thyroid), face, nasal cavity and palate under normal circumstances
  2. Acquisition of essential knowledge about the developmental defects/diseases of pharyngeal apparatus, face and palate
  3. Acquisition of the ability to distinguish the distinctive features of developmental anomalies/diseases of pharyngeal apparatus, face and palate
  4. Acquisition of essential knowledge about the development of respiratory tract and organs under normal circumstances
  5. Acquisition of the ability to correlate developmental stages of the lung and survival chance of the neonate
  6. Acquisition of essential knowledge about the developmental defects/diseases of respiratory tract and organs
  7. Acquisition of essential knowledge about the histology of respiratory system and the ability to correlate histological structure and function in respiratory system
  8. Acquisition of the ability to distinguish the distinctive histological features of respiratory system
Course Content- Derivatives of pharyngeal arches, pouches, grooves and membranes and their anomalies
- Development and anomalies of pharyngeal apparatus-related organs
- Development and anomalies of facial prominences, placodes, hillocks
- Development and anomalies of palate
- Development, anomalies/diseases and histology of respiratory tract and organs 
References1) KL Moore, TVN Persaud, MG Torchia. The Developing Human, Clinically Oriented Embryology
2) MH Ross, W Pawlina. Histology, A Text and Atlas. 

Course outline weekly

WeeksTopics
Week 1Development of pharyngeal apparatus Pharyngeal archs Arch cartilages Arch muscles Arch nerves Aortic archs
Week 2Pharyngeal pouches Auditory tube Palatine tonsil Thymus Parathyroid glands Ultimopharyngeal bodies
Week 3Pharyngeal grooves External acoustic meatus Cervical sinus, cervical fistula, cervical cyst Pharyngeal membranes Tympanic membrane
Week 4Development of pharyngeal apparatus-related organs Tongue, salivary gland, thyroid Bifid tongue Ectopic thyroid Thyroglossal duct cyst
Week 5Development of face, Facial-Frontonasal-Maxillary-Mandibular prominences, Lens placode-pit- vesicle, Otic placode-pit-vesicle, Auricular hillocks, Nasal placode-pit, Lateral & medial nasal prominences, Intermaxillary segment, Nasolacrimal duct,
Week 6- Development of palate, Separation of oral and nasal cavities, Primary palate, secondary palate, Palate/lip clefts, Classification in palate/lip and facial clefts
Week 7Midterm exam
Week 8- Development of respiratory tract and organs Laryngotracheal groove Respiratory diverticula Tracheoesophagial septum Agenesis, atresia and stenosis Tracheoesophagial fistula
Week 9- Developmental stages of lung, Pseudoglandular stage, Canalicular stage, Terminal sac stage, Alveolar stage - Correlation of developmental stages of lung and survival chance of the neonate Respiratory distress syndrome Lung hypoplasia
Week 10- Histology of nasal mucosa Nasal concha Epiglottis
Week 11- Histology of olfactory region
Week 12- Histology of middle ear, auditory tube and pharynx
Week 13- Histology of larynx - Histology of trachea
Week 14- Histology of bronchi and bronchioli, Histology of alveoli - Air-blood barrier
Week 15Preparation to final exam
Week 16Final exam

Assesment methods

Course activitiesNumberPercentage
Attendance285
Laboratory00
Application00
Field activities00
Specific practical training00
Assignments210
Presentation15
Project00
Seminar00
Midterms130
Final exam150
Total100
Percentage of semester activities contributing grade succes3250
Percentage of final exam contributing grade succes150
Total100

WORKLOAD AND ECTS CALCULATION

Activities Number Duration (hour) Total Work Load
Course Duration (x14) 14 2 28
Laboratory 0 0 0
Application000
Specific practical training000
Field activities000
Study Hours Out of Class (Preliminary work, reinforcement, ect)14570
Presentation / Seminar Preparation11212
Project000
Homework assignment2510
Midterms (Study duration)11010
Final Exam (Study duration) 12020
Total Workload3354150

Matrix Of The Course Learning Outcomes Versus Program Outcomes

D.9. Key Learning OutcomesContrubition level*
12345
1. Know the light and electron microscobic structure of the cells, tissues and organs; understanding the molecular and genetic components, establish the relationship between the structure function.   X 
2. Understanding of the molecular mechanisms regulating human embryonic development , should be able to define the developmental disorders.    X
3. Know the basic techniques such as histochemistry, immunohistochemistry, electron microscopy, cell culture.     
4. Must know and apply microscopic imaging techniques together and other quantitative methods such as stereology.     
5. Must have the basic knowledge and competence necessary to perform laboratuary works such as IVF, stem cell technologies in cooperation with the clinics.     
6. Must have knowledge, skills and attitudes that will contribute to education.    X
7. Should know how to obtain information to improve self and understand the importance of continuous learning.     
8. Be able to put forward original hypotheses independently; plan and write original projects.     
9. Have information and views on ethical issues on science and publication ethics and clinically related IVF and stem cell studies. X   
10. Be capable to participate in national and international scientific environments , make presentations and discussions.X    
11. Understand the evaluation criteria of the national and international journals and evaluate an article or project independently.  X   

*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest