SBT709 - MUSCULAR ADAPTATION TO EXERCISE

Course Name Code Semester Theory
(hours/week)
Application
(hours/week)
Credit ECTS
MUSCULAR ADAPTATION TO EXERCISE SBT709 1st Semester 3 0 3 10
PrequisitesNone
Course languageTurkish
Course typeElective 
Mode of DeliveryFace-to-Face 
Learning and teaching strategiesLecture
Discussion
Preparing and/or Presenting Reports
Project Design/Management
 
Instructor (s)A. Haydar Demirel, M.D., PhD 
Course objectiveThis course is designed to provide a broad but thorough understanding of the structural, physiological, biochemical basis of skeletal muscle relating to its development, functions and adaptations with various conditions. This course is designed to provide a broad but thorough understanding of the structural, physiological, biochemical and biomechanical basis of skeletal muscle relating to its development, functions and adaptations with various conditions.  
Learning outcomes
  1. Upon completion of the course students;
  2. Will improve his/her competency to understand and be able to discuss the relationships of muscle structure and contraction; muscle fibre type and its relationship to use
  3. Will comprehend the basis of acute and chronic skeletal muscle adaptations to varios exercise types and conditions includin microgravity and aging
  4. Will be able to placed on the development of experimental hypotheses in these areas of research
Course ContentThis course covers basic physiology and biochemistry of skeletal muscle. Topics include ultrastructure of skeletal muscle, mechanical and biochemical features of the crossbridge cycle in contraction, excitation contraction coupling, satellite cell and proliferation and differentiation of myoblasts, consideration of fiber type determination, its relationship to use, and the effects of hypertrophy and atrophy on muscle, mechanisms of disuse atrophy and skeletal muscle plasticity, muscle fatigue, mechanisms of muscular fatigue, the structure and functions of cytoskeleton, microgravity and skeletal muscle plasticity, aging, skeletal muscle properties, and recent advances in molecular adaptations.  
ReferencesBrian R. MacIntosh Skeletal Muscle: Form and Function Human Kinetics; 2 edition, 2006.
Richard Lieber Skeletal Muscle Structure, Function, and Plasticity: The Physiological Basis of Rehabilitation Skeletal Muscle Structure, Function, and Plasticity: Lippincott Williams & Wilkins; 2nd edition, 2002.
Andrew G. Engel . Myology McGraw-Hill Professional; 3 edition, 2004.
Brooks, G.A., T.D. Fahey, and K.M. Baldwin Exercise Physiology Human Bioenergetics and Its applications.. McGraw-Hill Companies; 4 edition Exercise Metabolism. Mark Hargreaves (Editor), 2. Edition. Human Kinetics, 2006.
 

Course outline weekly

WeeksTopics
Week 1Structure of the neuro-muscular system: muscle, motor neurons, and neuromuscular junctions
Week 2Structure of the neuro-muscular system: muscle, motor neurons, and neuromuscular junctions
Week 3Skeletal muscle function: neuromuscular transmission, muscle contraction, motor units and contractile proteins
Week 4The structure and functions of skeletal muscle cytoskeleton
Week 5Muscle phenotypes: fiber type detarminations by using histochemistry and MHC jel electrophoresis
Week 6Paper presentation and discussion related to muscle phenotype
Week 7Skeletal muscle satellite cell/injury and repair of the skeletal muscle
Week 8Paper discussion related to satellite cell
Week 9Midterm
Week 10Adaptation of the skeletal muscle to exercise training
Week 11Plasticity of skeletal muscle: microgravity, aging
Week 12Paper discussion related to last 2 weeks topic
Week 13Molecular mechanism of skeletal muscle hypertrophy, hyperplasia and atrophy
Week 14Musculer fatigue: Paper discussion and presentation related to hpertrophy, hyperplasia, atrophy and muscle fatigue
Week 15Preparation to final exam
Week 16Final exam

Assesment methods

Course activitiesNumberPercentage
Attendance140
Laboratory00
Application00
Field activities00
Specific practical training00
Assignments00
Presentation620
Project110
Seminar00
Midterms120
Final exam150
Total100
Percentage of semester activities contributing grade succes850
Percentage of final exam contributing grade succes150
Total100

WORKLOAD AND ECTS CALCULATION

Activities Number Duration (hour) Total Work Load
Course Duration (x14) 14 3 42
Laboratory 0 0 0
Application000
Specific practical training000
Field activities000
Study Hours Out of Class (Preliminary work, reinforcement, ect)148112
Presentation / Seminar Preparation6848
Project13636
Homework assignment000
Midterms (Study duration)13030
Final Exam (Study duration) 13232
Total Workload37117300

Matrix Of The Course Learning Outcomes Versus Program Outcomes

D.9. Key Learning OutcomesContrubition level*
12345
1. Develops and enhances specialized knowledge and competencies acquired in a Master's degree in movement and sport through literature and/or research.    X
2. Understands interdisciplinary interactions, reaching original results and knowledge by analyzing and synthesizing new and complex ideas.    X
3. Possesses necessary knowledge and technological skills in exercise and sport.    X
4. Recognizes the importance of ethical principles for individuals and society.  X  
5. Masters scientific research methods in exercise and sport.   X 
6. Plans and executes a research project; disseminates results through reports, articles, and presentations.    X
7. Critically analyzes, synthesizes, and evaluates new and complex ideas.   X 
8. Provides creative solutions to problems in using field-related technological equipment.    X
9. Introduces new thoughts, ideas, methodologies, and applications, contributing to the field's advancement.   X 
10. Takes a leading role in resolving interdisciplinary issues and problems.    X
11. Develops new ideas and methods using advanced cognitive processes for creative problem-solving.   X 
12. Leads and manages events and discussions on social relations and norms, facilitating necessary changes.  X  
13. Proficient in at least one European foreign language at C1 level for advanced communication.  X  
14. Addresses social, cultural, scientific, and ethical issues, contributing to societal advancement in movement and sport.  X  

*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest