KÄ°M635 - MASS SPECTROSCOPY
| Course Name | Code | Semester | Theory (hours/week) |
Application (hours/week) |
Credit | ECTS |
|---|---|---|---|---|---|---|
| MASS SPECTROSCOPY | KÄ°M635 | Any Semester/Year | 3 | 0 | 3 | 6 |
| Prequisites | none | |||||
| Course language | Turkish | |||||
| Course type | Elective | |||||
| Mode of Delivery | Face-to-Face | |||||
| Learning and teaching strategies | Lecture Question and Answer Preparing and/or Presenting Reports Demonstration Drill and Practice | |||||
| Instructor (s) | Prof. Dr. Bekir Salih | |||||
| Course objective | The purpose of this course is to inform the students about basics and components of mass spectrometry, interpretation and assessment of mass spectrum, resolution, tandem mass spectrometry (MS/MS),new generation mass spectrometry and recent developments in mass spectrometry. | |||||
| Learning outcomes |
| |||||
| Course Content | Introduction to mass spectrometry, vacuum systems, sample preparation techniques, sample introduction, basic components of mass spectrometry, interpretation of mass spectra, high resolution mass spectrometry, tandem mass spectrometry, mass spectrometry techniques for qualitative and quantitative analysis, recent developments in mass spectrometry. | |||||
| References | E. Hoffman, V. Stroobant, McGraw-Hill, ?Mass Spectrometry, Principles and Applications?, (2002). Gross J, ?Mass Spectrometry?, Springer-Verlag, (2002). Chapman, J. R., (Ed.), ?Protein and Peptide Analysis by Mass Spectrometry, Methods in Molecular Biology?, Vol. 61, Humana Press, Totowa, NJ, (1996). Dass C, ?Fundamentals of Contemporary Mass Spectrometry?, (2007). Brymner R, Penney J.R, ?Mass Spectrometry?, (1968) | |||||
Course outline weekly
| Weeks | Topics |
|---|---|
| Week 1 | Basics of mass spectrometry |
| Week 2 | Mass spectrometry and vacuum systems |
| Week 3 | Sample preparation techniques and sample introduction |
| Week 4 | Components of mass spectrometric systems, ionization sources |
| Week 5 | Mass analyzer, detectors, resolution in mass spectrometry |
| Week 6 | Interpretation of mass spectrum, isotope effects |
| Week 7 | Midterm Exam |
| Week 8 | High resolution systems |
| Week 9 | Tandem mass spectrometry (MS/MS) |
| Week 10 | Hyphenated mass spectrometric techniques |
| Week 11 | Mass spectrometric investigation of molecules with high molecular mass |
| Week 12 | Biological mass spectrometry |
| Week 13 | Quantitation in mass spectrometry |
| Week 14 | Drill and practice |
| Week 15 | Preparation for Final Exam |
| Week 16 | Final exam |
Assesment methods
| Course activities | Number | Percentage |
|---|---|---|
| Attendance | 0 | 0 |
| Laboratory | 0 | 0 |
| Application | 2 | 5 |
| Field activities | 0 | 0 |
| Specific practical training | 0 | 0 |
| Assignments | 10 | 25 |
| Presentation | 0 | 0 |
| Project | 0 | 0 |
| Seminar | 0 | 0 |
| Midterms | 1 | 20 |
| Final exam | 1 | 50 |
| Total | 100 | |
| Percentage of semester activities contributing grade succes | 13 | 50 |
| Percentage of final exam contributing grade succes | 1 | 50 |
| Total | 100 | |
WORKLOAD AND ECTS CALCULATION
| Activities | Number | Duration (hour) | Total Work Load |
|---|---|---|---|
| Course Duration (x14) | 14 | 3 | 42 |
| Laboratory | 0 | 0 | 0 |
| Application | 2 | 4 | 8 |
| Specific practical training | 0 | 0 | 0 |
| Field activities | 0 | 0 | 0 |
| Study Hours Out of Class (Preliminary work, reinforcement, ect) | 14 | 2 | 28 |
| Presentation / Seminar Preparation | 0 | 0 | 0 |
| Project | 0 | 0 | 0 |
| Homework assignment | 10 | 5 | 50 |
| Midterms (Study duration) | 1 | 20 | 20 |
| Final Exam (Study duration) | 1 | 40 | 40 |
| Total Workload | 42 | 74 | 188 |
Matrix Of The Course Learning Outcomes Versus Program Outcomes
| D.9. Key Learning Outcomes | Contrubition level* | ||||
|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | |
| 1. Develops and deepens their knowledge in the field of natural sciences based on the chemistry bachelor level qualifications. | X | ||||
| 2. Determines interdisciplinary interactions by analyzing information obtained from advanced scientific research. | X | ||||
| 3. Utilizes advanced theoretical and applied knowledge in their field. | X | ||||
| 4. Relates basic and advanced knowledge in their field and proposes interdisciplinary new ideas. | X | ||||
| 5. Develops scientific solution proposals and strategies using their theoretical and applied knowledge in the field. | X | ||||
| 6. Conducts individual and/or group work in research requiring expertise in their field. | X | ||||
| 7. Takes initiative to solve problems encountered in individual or group work related to their field. | X | ||||
| 8. Participates in interdisciplinary studies with their basic knowledge and analytical thinking skills. | X | ||||
| 9. Identifies lacks by monitoring scientific developments in their field and manage learning processes to conduct advanced research. | X | ||||
| 10. Accesses foreign sources in their field using at least one foreign language, updates their knowledge, and communicates with colleagues worldwide. | X | ||||
| 11. Manages data collection, interpretation, application, and dissemination processes related to their field effectively and safely while considering societal, scientific, cultural, and ethical values. | X | ||||
*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest