BYM713 - BIOORGANIC CHEMISTRY IN LIFE SCIENCES

Course Name Code Semester Theory
(hours/week)
Application
(hours/week)
Credit ECTS
BIOORGANIC CHEMISTRY IN LIFE SCIENCES BYM713 Any Semester/Year 3 0 3 9
Prequisites-
Course languageTurkish
Course typeElective 
Mode of DeliveryFace-to-Face 
Learning and teaching strategiesLecture
Discussion
Question and Answer
 
Instructor (s)Assoc. Prof. Dr. Lokman Uzun 
Course objectiveThe aim of the course is to give basic knowledge about organic chemistry to the student, to learn the fundamental organic reactions in biological systems and organic pathways of biomolecules. 
Learning outcomes
  1. ? Basic principles of organic chemistry ? Oxygene and sulphur containing simple molecules, ? Organic compounds in view of frame of biological science, ? Molecular shape and structural properties, ? Reaction bringing lifes to molecules, ? Bioorganic chemical reactions of amino acids and polypeptides, ? Bioorganic chemical reactions of phospahte groups and polynucleotides, ? Enzyme chemistry and models, ? Function and importance of metal ions in organic processes.
Course ContentThe content of the course is to give basic knowledge about organic chemistry to the student, simple heteroatomic compounds, organic molecules in view of biological science, relation between shape and structure, basic reaction in life science, biooragnic reactions of biomolecules, enzymes and their kinetic models, metal ions in organic reactions.  
References? Ders notları
? Güncel yayınlar
? D.L Nelson and M.M. Cox, ?Lehninger Principles of Biochemistry? 4th ed., W.H Freeman, (2005), NY, USA. (İngilizce baskı ve Türkçe çeviri (3. baskı))
? J. Crowe, T. Bradshaw, ?Chemistry for the Biosciences: The Essential Concepts?, 2nd Ed. (2010), Oxford Univesity Press Inc., USA.
? H. Dugas, ?Bioorganic Chemistry a Chemical Approach to Enzyme Action?, 3rd Ed., (1996), Springer-Verlag, N.Y., USA.
? P.W. Groundwater, G.A. Taylor, Organic Chemistry for Students of Health and Life Sciences?, 4th Ed., (1997), Pearson Education Ltd., Essex, England.
 

Course outline weekly

WeeksTopics
Week 1First meeting and general information about course and its structure
Week 2Basic Principles in Bioorganic Chemistry: Atomic-Molecular Structure / Nomenclature / Stereochemistry and Mechanism
Week 3Oxygene and Sulphur Containing Simple Organic Compounds: Alcohols ? Phenols ? Ethers and Their sulphur analogs ? Carbonyl Compounds: Aldehydes ? Ketones ? Carboxylic Acids and their Derivatives ? Nitrogene Compounds: Amines
Week 4Bioorganic Compounds: Carbohydrates ? Amino Acids/Protens ? Aromatic Compounds/Nucleic Acids ? Lipids and Fatty Acids
Week 5Molecular Interactions: Holding it all together ? Organic Compounds: the framework of life
Week 6Molecular Shape and Structure Isomerism
Week 7Chemical Analysis ? Energy ? Kinetic ? Equilibrium ? Acids, Bases, and the Aqueous Environment: the medium of life
Week 8Chemical Reactions: Bringing molecules to life ? Chemical Reactions: reaction mechanism driving the chemistry of life
Week 9Bioorganic Chemistry of Amino Acids and Polypeptides ? Biooragnic Chemistry of Phosphate Groups and Polynucleotides
Week 10Enzyme Chemsitry and Enzyme Models ? Metal Ions and Coenzyme Chemistry
Week 11Mid-Term
Week 12Student presentation (hot topics in bioorganic chemistry)
Week 13Student presentation (hot topics in bioorganic chemistry)
Week 14Student presentation (hot topics in bioorganic chemistry)
Week 15Preparation to final exam
Week 16Final exam

Assesment methods

Course activitiesNumberPercentage
Attendance1414
Laboratory00
Application00
Field activities00
Specific practical training00
Assignments00
Presentation35
Project00
Seminar15
Midterms125
Final exam150
Total99
Percentage of semester activities contributing grade succes150
Percentage of final exam contributing grade succes150
Total100

WORKLOAD AND ECTS CALCULATION

Activities Number Duration (hour) Total Work Load
Course Duration (x14) 14 3 42
Laboratory 0 0 0
Application000
Specific practical training000
Field activities000
Study Hours Out of Class (Preliminary work, reinforcement, ect)14798
Presentation / Seminar Preparation41248
Project000
Homework assignment000
Midterms (Study duration)13535
Final Exam (Study duration) 14747
Total Workload34104270

Matrix Of The Course Learning Outcomes Versus Program Outcomes

D.9. Key Learning OutcomesContrubition level*
12345
1. Ability to understand and implement pure sciences, mathematics and engineering in higher level,    X
2. Ability to conduct intra- and inter-disciplinary studies; to gain required methodological skills for conducting the research,    X
3. Ability to analyse, synthesize and evaluate the current ideas and developments in the specialized area,    X
4. To have a qualification to conduct a comprehensive research that bringing new insights into science and technology, that leading to a novel methodology or technological product/process; or that leveraging a known methodology to another area,  X  
5. To contribute to the scientific and technological literature by disseminating the outcomes of scientific studies in international and national academic grounds,  X  
6. To evaluate the scientific, technological and social developments and to transfer them to the society by considering scientific neutrality and ethical responsibility,  X  
7. Ability to have a verbal and written communication skills in at least one foreign language at a European Language Portfolio C1 General Level,    X
8. Ability to understand theeffects of engineering solutions and practice in the problems related to the biological systems and to build awareness of the legal outcomes.X    

*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest