BYM702 - BIOLOGICAL SCIENCES-II

Course Name Code Semester Theory
(hours/week)
Application
(hours/week)
Credit ECTS
BIOLOGICAL SCIENCES-II BYM702 Spring 3 0 3 9
PrequisitesBiological Sciences-I
Course languageTurkish
Course typeElective 
Mode of DeliveryFace-to-Face 
Learning and teaching strategiesLecture
Discussion
Question and Answer
 
Instructor (s)Prof. Dr. A.K. PiÅŸkin/Assoc. Prof. Dr. A. Taner/Dr. E. Çelik-Akdur 
Course objectiveTo introduce students from engineering and basic sciences background to the basic concepts of biochemistry, microbiology and molecular biology and its applications. 
Learning outcomes
  1. ? To explain the structural properties of biological macromolecule units.
  2. ? To give examples of functions of biomolecules in living systems.
  3. ? To compare various biomolecules in terms of solubility and size.
  4. ? To plan biotechnological applications taking into account the binding properties of biomolecules.
  5. ? To understand the microbial diversity of microbial classification.
  6. ? To learn the isolation and identification of microorganisms from various samples, such as of food and clinical origin.
  7. ? To give information about the interaction between humans and microorganisms.
  8. ? To provide information about the mechanism of action of anti-microbial agents on microbes. ? To understand the manipulations and interactions of biological macromolecules.
Course ContentThe course will cover three main areas: biochemistry, microbiology and molecular biology. Biomolecules, their units, bonding involved in polymerization, and functional groups will be discussed. Structural properties of DNA and RNA will be described. Lipids will be grouped, the structural and functional properties will be discussed. The structural and functional characteristics of carbohydrates will be examplified. Proteins and the importance of conformational changes will be explained. Biomolecules will be compared in terms of solubility and size; and information will be given on their bioengineering applications. Microbiology is the basis of scientific and technological applications of higher-order organisms. Detailed information will be given on the structures and types of microorganisms. In the molecular biology section, interactions and manipulations of the macromolecules DNA, RNA and proteins will be covered and examples from its industrial applications will be given. 
References1. D.Nelson, M. Cox, Lehninger Principles of Biochemistry, 5th ed., W.H. Freeman, 2009.
2. The third edition of Microbiology, A Systems Approach: Marjorie Kelly Cowan. Mc Graw Hill, USA, 2012.
3. Review of Medical Microbiology and Immunology, Warren Levınsom, 11 Edition, Cowan. Mc Graw Hill, Lange, USA, 2010.
4. Mikrobiyoloji, Richard A. Havey & Pamela A. Champe , Nobel Tıp Kitabevleri, Turkye 2006
5. http://medicalppt.blogspot.com/2009/02/microbiology-powerpoint-lectures.html
6. http://www.life.umd.edu/classroom/bsci424/BSCI223WebSiteFiles/LectureList.htm
7. B. Alberts et al. Molecular Biology of the Cell, 5th ed., Garland Science, NY, 2007.
8. M. Konuk, Moleküler Biyoloji. 2. baskıdan çeviri. Nobel Yayınları, 2004. 

Course outline weekly

WeeksTopics
Week 1General properties of biomolecules, nucleic acids
Week 2Protein biochemistry
Week 3Lipids, their types and functions
Week 4Carbohydrates and their importance in biological systems. Bioengineering applications of biomolecules
Week 5A general presentation on the microbial diversity of the microbial world
Week 6The role of microbes in our lives
Week 7Different methods for microbial diagnosis in the microbiology laboratory
Week 8The effects of antimicrobial agents on the microbes
Week 91st midterm exam
Week 10DNA replication, the flow of genetic information and mutations
Week 11Gene manipulations and recombinant DNA technology
Week 12Protein synthesis and post-translational events
Week 13Protein purification and analysis
Week 14Discussion and paper presentations
Week 15Preparation to final exam
Week 16Final exam

Assesment methods

Course activitiesNumberPercentage
Attendance00
Laboratory00
Application00
Field activities00
Specific practical training00
Assignments00
Presentation120
Project120
Seminar00
Midterms120
Final exam140
Total100
Percentage of semester activities contributing grade succes160
Percentage of final exam contributing grade succes140
Total100

WORKLOAD AND ECTS CALCULATION

Activities Number Duration (hour) Total Work Load
Course Duration (x14) 14 3 42
Laboratory 0 0 0
Application000
Specific practical training000
Field activities000
Study Hours Out of Class (Preliminary work, reinforcement, ect)12560
Presentation / Seminar Preparation14040
Project14848
Homework assignment000
Midterms (Study duration)13030
Final Exam (Study duration) 15050
Total Workload30176270

Matrix Of The Course Learning Outcomes Versus Program Outcomes

D.9. Key Learning OutcomesContrubition level*
12345
1. Ability to understand and implement pure sciences, mathematics and engineering in higher level,   X 
2. Ability to conduct intra- and inter-disciplinary studies; to gain required methodological skills for conducting the research,    X
3. Ability to analyse, synthesize and evaluate the current ideas and developments in the specialized area,  X  
4. To have a qualification to conduct a comprehensive research that bringing new insights into science and technology, that leading to a novel methodology or technological product/process; or that leveraging a known methodology to another area,   X 
5. To contribute to the scientific and technological literature by disseminating the outcomes of scientific studies in international and national academic grounds,    X
6. To evaluate the scientific, technological and social developments and to transfer them to the society by considering scientific neutrality and ethical responsibility,    X
7. Ability to have a verbal and written communication skills in at least one foreign language at a European Language Portfolio C1 General Level, X   
8. Ability to understand theeffects of engineering solutions and practice in the problems related to the biological systems and to build awareness of the legal outcomes.    X

*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest