BÄ°S621 - EXPERIMENTAL DESIGN

Course Name Code Semester Theory
(hours/week)
Application
(hours/week)
Credit ECTS
EXPERIMENTAL DESIGN BÄ°S621 2nd Semester 3 0 3 7
PrequisitesHaving successfully completed the lectures BIS 605 or BIS 735
Course languageTurkish
Course typeElective 
Mode of DeliveryFace-to-Face 
Learning and teaching strategiesLecture
Discussion
 
Instructor (s)ASSIST. PROF. SEVÄ°LAY KARAHAN, PHD 
Course objectiveTo teach experimental design techniques and to enable students to choose the most appropriate design technique that minimizes the experimental error, to model the design and to test hypothesis on model parameters. To enable students to use different softwares and by using these programs to test hypothesis about one factor and factorial designs with random, fixed and mixed effect models on different data sets and interpret the results. 
Learning outcomes
  1. Students; Know different experimental design techniques and can decide on the most appropriate design for a specific research.
  2. Can write the model equation for the selected design technique.
  3. Can test model parameters.
  4. Can use different softwares and interpret the output.
Course ContentPrinciples of experimental design, randomization, experimental error and ways of minimizing experimental error, experiments with one factor, block designs, Latin and GrecoLatin Square techniques, factorial experiments, cross over designs and covariance analysis.  
References1. Montgomery, DC., Design and Analysis of Experiments, John Wiley and Sons, Inc., New York, 1984.
2. Mason, RL., Gunst, RF., Hess, JL., Statistical Design and Analysis of Experiments, John Wiley and Sons, Inc., New York, 1989.
3. Diaz, AG., Phillips, DT., Principles of Experimental Design and Analysis. Chapman and Hall, London, 1985.
4. Hicks, CR., Fundamental Concepts in the Design of Experiments. 2nd. ed., Holt, Rinehart and Winston, New York, 1973.
5. Conover, WJ., Practical Nonparametric Statistics. 2nd ed., John Wiley and Sos Inc., New York, 1982. 

Course outline weekly

WeeksTopics
Week 1Introduction, sources of experimental error, randomization and constraints on randomization.
Week 2Single factor experiment-One way analysis of variance
Week 3Single factor, completely randomized design. Assumptions, testing the validity of assumptions, alternative solutions in case of failure in validating assumptios.
Week 4Complete randomized block design, parametric and nonparametric approaches.
Week 5Incomplete randomized block design.
Week 6Midterm exam
Week 7Latin Square and greko latin square designs.
Week 8Factorial experiments. Interaction.
Week 9Fixed, random and mixed effect models.
Week 102n factorial experiment.
Week 11Midterm exam
Week 123n factorial experiment
Week 13Cross over designs.
Week 14Covariance analysis
Week 15Preparation to final exam
Week 16Final Exam

Assesment methods

Course activitiesNumberPercentage
Attendance00
Laboratory00
Application00
Field activities00
Specific practical training00
Assignments610
Presentation215
Project00
Seminar00
Midterms225
Final exam150
Total100
Percentage of semester activities contributing grade succes1050
Percentage of final exam contributing grade succes150
Total100

WORKLOAD AND ECTS CALCULATION

Activities Number Duration (hour) Total Work Load
Course Duration (x14) 14 3 42
Laboratory 0 0 0
Application2714
Specific practical training000
Field activities000
Study Hours Out of Class (Preliminary work, reinforcement, ect)14570
Presentation / Seminar Preparation21530
Project000
Homework assignment6424
Midterms (Study duration)21020
Final Exam (Study duration) 11010
Total Workload4154210

Matrix Of The Course Learning Outcomes Versus Program Outcomes

D.9. Key Learning OutcomesContrubition level*
12345
1. A specialist with a graduate diploma in biostatistics: Has the knowledge to lead research planning, execution, and finalization, staying updated on literature and current studies.     X
2. Critically evaluates studies and scientific papers in presentations, courses, seminars, and conferences, encouraging a critical perspective.   X 
3. Has the sufficient theoretical and practical knowledge of statistics to determine the appropriate statistical analysis and to grasp the results correctly.    X
4. Be proficient in computer use and statistical software, ensuring data suitability and recommending solutions for data management and analysis methods.    X 
5. Effectively communicates analysis issues through active participation in discussions, exchanging information with the advisor, and presenting seminars.    X
6. Provides method suggestions in consultancy, does research planning, prepares research reports.    X
7. Maintains scientific accuracy and ethical values, remaining careful against any conscious or unconscious biases throughout the study.    X
8. Supports a counseling service under faculty supervision, may handle independent projects, and participates in conferences, presenting papers or posters with the academic advisor.  X  
9. Be ready for multidisciplinary studies, collaborating professionally in group settings and gains the ability to assign individuals in the group.    X
10. Integrates diverse disciplines to analyze and synthesize information, offering solutions.    X

*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest