BÄ°S608 - ADVANCED BIOSTATISTICAL ANALYSIS

Course Name Code Semester Theory
(hours/week)
Application
(hours/week)
Credit ECTS
ADVANCED BIOSTATISTICAL ANALYSIS BÄ°S608 2nd Semester 3 0 3 6
PrequisitesHaving successfully completed the lectures BIS 605 or BIS 735
Course languageTurkish
Course typeElective 
Mode of DeliveryFace-to-Face 
Learning and teaching strategiesLecture
Discussion
 
Instructor (s)PROF. ERDEM KARABULUT, PHD - PROF. PINAR ÖZDEMÄ°R, PHD 
Course objectiveTo teach the advanced biostatistical methods in addition to the basics of biostatistics.  
Learning outcomes
  1. Students; learn the basic concepts of advanced biostatistical methods,
  2. use the appropriate methods correctly,
  3. interpret the results of the analysis correctly.
Course Content1. Descriptive statistics: Central tendency, measures of location and dispersion,
2. Measures of risk and hypothesis tests regarding these measures,
3. Sample size,
4. Life tables, calculating expected lifetime,
5. Logistic, probit, Poisson and Cox proportional hazard regression. 
References1. Lachin J.M., Biostatistical methods, John WiÅŸley & Sons Inc. 2000
2. Dowson B., Biostatistics, Lange Medical Books/McGraw Hill, 2001
3. Woolson R.F., Statistical Methods For The Analysis Of Biomedical Data, John Wiley & Sons Inc. 1987 

Course outline weekly

WeeksTopics
Week 1Descriptive statistics: Central tendency, measures of location and dispersion
Week 2Measures of Risk
Week 3Statistical Distributions
Week 4Overview of Hypothesis Tests
Week 5Hypothesis tests related to descriptive statistics and measures of risk
Week 6Calculating required sample size
Week 7Building Lifetables and calculating expected lifetime
Week 8Basic estimation methods used in survival analysis
Week 9Midterm exam
Week 10Overview of regression and correlation
Week 11Logistic Regression
Week 12Probit Regression
Week 13Poisson Regression and Negative Binomial Regression
Week 14Cox Proportional Hazard Regression
Week 15Preparation to final exam
Week 16Final exam

Assesment methods

Course activitiesNumberPercentage
Attendance00
Laboratory00
Application00
Field activities00
Specific practical training00
Assignments310
Presentation115
Project00
Seminar00
Midterms125
Final exam150
Total100
Percentage of semester activities contributing grade succes550
Percentage of final exam contributing grade succes150
Total100

WORKLOAD AND ECTS CALCULATION

Activities Number Duration (hour) Total Work Load
Course Duration (x14) 14 3 42
Laboratory 0 0 0
Application000
Specific practical training000
Field activities000
Study Hours Out of Class (Preliminary work, reinforcement, ect)14228
Presentation / Seminar Preparation12020
Project000
Homework assignment31545
Midterms (Study duration)11515
Final Exam (Study duration) 13030
Total Workload3485180

Matrix Of The Course Learning Outcomes Versus Program Outcomes

D.9. Key Learning OutcomesContrubition level*
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*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest