EFT685 - UNIT OPERATIONS IN PHARMACEUTICAL TECHNOLOGY
| Course Name | Code | Semester | Theory (hours/week) |
Application (hours/week) |
Credit | ECTS |
|---|---|---|---|---|---|---|
| UNIT OPERATIONS IN PHARMACEUTICAL TECHNOLOGY | EFT685 | 1st Semester | 3 | 0 | 3 | 7 |
| Prequisites | ||||||
| Course language | Turkish | |||||
| Course type | Must | |||||
| Mode of Delivery | Face-to-Face | |||||
| Learning and teaching strategies | Lecture Discussion | |||||
| Instructor (s) | Prof. Dr. Sevda Åženel, Prof.Dr. Selma Åžahin | |||||
| Course objective | To give information about unit processes used in pharmaceutical technology and their applications Technology | |||||
| Learning outcomes |
| |||||
| Course Content | Dosage forms; Unit Operations; Validation; Examples to applications | |||||
| References | 1. Larry L. Augsburger, Stephen W. Hoag (Eds.), Pharmaceutical dosage forms: Tablets (3rd Ed), Vol 1: Unit Operations and Mechanical Properties, Informa Healthcare, New York, 2008. 2. Takayuki Shioiri, Kunisuke Izawa, Toshiro Konoike (Eds.), Pharmaceutical Process Chemistry, Wiley-VCH, Singapore, 2011. 3. Beverly Nickerson (Ed.), Sample Preparation of Pharmaceutical Dosage Forms: Challenges and Strategies for Sample Preparation and Extraction, AAPSPress, New York, 2010. 4. Thomas M. Jacobsen, Albert I. Wertheimer (Eds.), Modern Pharmaceutical Industry, Jones and Bartlett Publishers, USA, 2010. 5. Sudhakara Reddy Pondugula, M. Gopal Rao, Govinda Rajan Gudala, R. Vamsi Krishna, Pharmaceutical Engineering: Practical Manual (Unit Operations), Pharma Book Syndicate, India, 2007. 6. K Sambamurthy, Pharmaceutical Engineering, New Age International Publishers, New Delhi, 2005. 7. Lecture notes 8. Research articles 9. Websites of scientific and legal organizations | |||||
Course outline weekly
| Weeks | Topics |
|---|---|
| Week 1 | Introduction to Unit Operations |
| Week 2 | Basic Unit Operations: Particle size and methods for particle size determination |
| Week 3 | Basic Unit Operations: Milling, Sieving, Mixing |
| Week 4 | Basic Unit Operations: Filtration |
| Week 5 | Basic Unit Operations: Coating,Drying |
| Week 6 | Basic Unit Operations: Sterilisation, Parametric Release |
| Week 7 | Validation, Good Manufacturing Proceses (GMP) |
| Week 8 | Midterm exam |
| Week 9 | Introduction to Pharmaceutical Dosage Forms |
| Week 10 | Applications: Unit operations in liquid dosage forms |
| Week 11 | Applications: Unit operations in solid dosage forms (tablets, capsules etc.) |
| Week 12 | Applications: Unit operations in semi solid dosage forms |
| Week 13 | Application: Unit operations in Sterile products |
| Week 14 | Quality by Design (QbD) |
| Week 15 | Preparation for the Final Exam |
| Week 16 | Final Exam |
Assesment methods
| Course activities | Number | Percentage |
|---|---|---|
| Attendance | 0 | 0 |
| Laboratory | 0 | 0 |
| Application | 0 | 0 |
| Field activities | 0 | 0 |
| Specific practical training | 0 | 0 |
| Assignments | 0 | 0 |
| Presentation | 0 | 0 |
| Project | 0 | 0 |
| Seminar | 0 | 0 |
| Midterms | 1 | 50 |
| Final exam | 1 | 50 |
| Total | 100 | |
| Percentage of semester activities contributing grade succes | 1 | 50 |
| Percentage of final exam contributing grade succes | 1 | 50 |
| Total | 100 | |
WORKLOAD AND ECTS CALCULATION
| Activities | Number | Duration (hour) | Total Work Load |
|---|---|---|---|
| Course Duration (x14) | 14 | 3 | 42 |
| Laboratory | 0 | 0 | 0 |
| Application | 0 | 0 | 0 |
| Specific practical training | 0 | 0 | 0 |
| Field activities | 0 | 0 | 0 |
| Study Hours Out of Class (Preliminary work, reinforcement, ect) | 14 | 5 | 70 |
| Presentation / Seminar Preparation | 0 | 0 | 0 |
| Project | 0 | 0 | 0 |
| Homework assignment | 0 | 0 | 0 |
| Midterms (Study duration) | 1 | 36 | 36 |
| Final Exam (Study duration) | 1 | 60 | 60 |
| Total Workload | 30 | 104 | 208 |
Matrix Of The Course Learning Outcomes Versus Program Outcomes
| D.9. Key Learning Outcomes | Contrubition level* | ||||
|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | |
*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest