BYL607 - SURGICAL METHODS of EXPERIMENTAL ANIMALS
| Course Name | Code | Semester | Theory (hours/week) |
Application (hours/week) |
Credit | ECTS |
|---|---|---|---|---|---|---|
| SURGICAL METHODS of EXPERIMENTAL ANIMALS | BYL607 | 1st Semester | 2 | 4 | 3 | 10 |
| Prequisites | NONE | |||||
| Course language | Turkish | |||||
| Course type | Elective | |||||
| Mode of Delivery | Face-to-Face | |||||
| Learning and teaching strategies | Question and Answer Preparing and/or Presenting Reports Experiment | |||||
| Instructor (s) | Assoc. Prof. Esin Çetin | |||||
| Course objective | Teaching to basic surgical techniques in experimental animals | |||||
| Learning outcomes |
| |||||
| Course Content | Basic manupilation of experimental animals Anesthesia techniques Eutonasi Basic stur techniques in vivo tissue perfusion Subcutan implantation Ovarectomy Determination of eustrus Biopsy of testis Collections of sperm Recording physiological data in rats | |||||
| References | Principles of Laboratory Animal Science, Elsevier Sci. Pub., L.F.M Van Zutphen eds., New York, 1993 Introduction to Laoratory Animal Science and Technology, J.K. Inglis, Pergamon Press, GB, 1980 | |||||
Course outline weekly
| Weeks | Topics |
|---|---|
| Week 1 | Introduction to an experimental animal laboratory, the physical properties, animal cage, housing and maintanence (T) Understatement of operations in experimental animal laboratory, to see the sorts of animal cages, taking the animal out of cage, weig |
| Week 2 | The races of experimental animals, production of the animals and their prosperities (T) Holding technicques of experimental animals. Holding of mouse, rat, cavy and rabbit (P) |
| Week 3 | Preoperative and postoperative preparation of the experimental animals. Utilization of surgical tools (T) Holding technicques of mouse, rat, cavy and rabbit (P) |
| Week 4 | Anaesthesia and euthanasia on experimental animals. Fundamental of stur techniques. Marking of experimental animal groups (T) Injection techniques I: Intradermic and subdermic injection techniques. |
| Week 5 | Experimental animal anatomy and histology (T) Injection techniques II: Application intraperitonal, intramuscular, intraveous injection (P) |
| Week 6 | Experimental animal physiology (T) Anhestesia application on rat, rectal temperature measurement. Heating the animal in the case of hypotermia and recovery. Sturing on an animal model (P). |
| Week 7 | Ethical concepts on experimental animals and alternative methods to the animal studies (T) Blood collecting methods on rats, blood collecting from heart (P) |
| Week 8 | Planning the experiments to be done (T) In vivo tissue perfusion (total liver and kidney perfusion) (without sterilization) (P) |
| Week 9 | Quarantine on experimental animals, internal and external parasites, essencial laboratory safety (T) In vivo blood pressure measurements of rat, and the observation of the blood pressure changes because of different substances given into the femoral |
| Week 10 | Autopsy in experimental animals (T) Recognition of internal and external parasites of experimental animals. Application of autopsy (innards observation and physical appearence) (P) |
| Week 11 | Legal arrangenents of laboratry animals in our country and in the world (T) Subcutaneous device implantation (data logger implantation), postoperative maintance (under steril conditions) (P) |
| Week 12 | Biochemistry of experimental animals (T) Ovariectomy (under steril conditions) (P) |
| Week 13 | Ethical rules and completing an ethical commission application form (T) Determination of eustrous cycle of rat, testis biopsy and sperm collecting, in vivo sperm collection (without coagulation) |
| Week 14 | Presentations (T) Recording the physiological data of rat. Recording the respiration rate and depth, ECG recording, EEG recording (P) |
| Week 15 | Studying for final exam |
| Week 16 | Final Exam |
Assesment methods
| Course activities | Number | Percentage |
|---|---|---|
| Attendance | 0 | 0 |
| Laboratory | 0 | 0 |
| Application | 0 | 0 |
| Field activities | 0 | 0 |
| Specific practical training | 0 | 0 |
| Assignments | 0 | 0 |
| Presentation | 0 | 0 |
| Project | 0 | 0 |
| Seminar | 0 | 0 |
| Midterms | 1 | 50 |
| Final exam | 1 | 50 |
| Total | 100 | |
| Percentage of semester activities contributing grade succes | 1 | 50 |
| Percentage of final exam contributing grade succes | 1 | 50 |
| Total | 100 | |
WORKLOAD AND ECTS CALCULATION
| Activities | Number | Duration (hour) | Total Work Load |
|---|---|---|---|
| Course Duration (x14) | 14 | 2 | 28 |
| Laboratory | 14 | 4 | 56 |
| Application | 0 | 0 | 0 |
| Specific practical training | 0 | 0 | 0 |
| Field activities | 0 | 0 | 0 |
| Study Hours Out of Class (Preliminary work, reinforcement, ect) | 14 | 13 | 182 |
| Presentation / Seminar Preparation | 1 | 10 | 10 |
| Project | 0 | 0 | 0 |
| Homework assignment | 0 | 0 | 0 |
| Midterms (Study duration) | 0 | 0 | 0 |
| Final Exam (Study duration) | 1 | 10 | 10 |
| Total Workload | 44 | 39 | 286 |
Matrix Of The Course Learning Outcomes Versus Program Outcomes
| D.9. Key Learning Outcomes | Contrubition level* | ||||
|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | |
| 1. Improves knowledge in proficiency level based on the undergraduate level in biology or different disciplines by using scientific methods to analyse and interpret it. | X | ||||
| 2. Uses theoretical and practical knowledge obtained from his/her field in proficiency level | X | ||||
| 3. Interprets the knowledge obtained from his/her field with integrating the acquired knowledge from the other disciplines and synthesize new knowledge. | X | ||||
| 4. Gain ability to solve problems in his/her using research methods. | X | ||||
| 5. Gain ability to conduct study independently required in his/her field of specialization. | X | ||||
| 6. Improves new strategies to solve complex problems in the field of specialization. | X | ||||
| 7. Uses acquired proficiency level knowledge and skills in processes of learning in his/her field. | X | ||||
| 8. Uses computer software with computer technologies that is required in his/her field. | X | ||||
| 9. Has the ability of minding social, scientific, cultural and ethical values in the levels of collecting, interpreting and applying the data in his/her field. | X | ||||
| 10. Evaluates the important events and cases by minding the results which take part in the development of his/her field. | X | ||||
*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest