KÄ°M658 - STEREOCHEMISTRY
| Course Name | Code | Semester | Theory (hours/week) |
Application (hours/week) |
Credit | ECTS |
|---|---|---|---|---|---|---|
| STEREOCHEMISTRY | KÄ°M658 | Any Semester/Year | 3 | 0 | 3 | 6 |
| Prequisites | none | |||||
| Course language | Turkish | |||||
| Course type | Elective | |||||
| Mode of Delivery | Face-to-Face | |||||
| Learning and teaching strategies | Lecture Discussion Question and Answer Preparing and/or Presenting Reports | |||||
| Instructor (s) | Prof. Dr. Barış Temelli | |||||
| Course objective | Course objective Aim of this course is to give informations about classification and naming of stereoisomers, techniques of separation and purification, and stereochemistry of organic reactions and emphasize how important stereoisomers in drug research. | |||||
| Learning outcomes |
| |||||
| Course Content | Chemical structure and symmetry, stereoisomer, enantiomers, diastereomers, separation of isomers, Determination of configuration and asymmetric synthesis | |||||
| References | Eliel E.L., Wilen S.H., Doyle M.P.(2001), Basic Organic Stereochemistry? John Wiley, New York. Robinson M.J.T. (1999), Organic Sterochemistry, Oxford University Pres. Kettle S.F.A.(1995), Symmetry and Structure, John Wiley&Sons, 1995. Vincent Alan, Molecular Symmetry and Group Theory, John Wiley&Sons, 1996. reviews and journals | |||||
Course outline weekly
| Weeks | Topics |
|---|---|
| Week 1 | General concepts in organic stereochemistry |
| Week 2 | Conformation of cyclic molecules |
| Week 3 | Topological and supramolecular stereochemistry |
| Week 4 | Structure: Conformation, constitution |
| Week 5 | Stereoisomers, racemisation and naming optical isomers |
| Week 6 | presentation |
| Week 7 | Stereochemical analysis: determination of relative and absolute configuration(x-ray, IR-, NMR etc.) |
| Week 8 | Determination of enantiomer and diastereomer composition |
| Week 9 | presentation |
| Week 10 | 10. Symmetry and stereochemistry |
| Week 11 | Separation of stereoisomers, resolution and racemization |
| Week 12 | Separation of stereoisomers, resolution and racemization |
| Week 13 | Stereochemistry of organic reactions-I |
| Week 14 | Stereochemistry of organic reactions-II |
| Week 15 | Preparation for exam |
| Week 16 | Final exam |
Assesment methods
| Course activities | Number | Percentage |
|---|---|---|
| Attendance | 0 | 0 |
| Laboratory | 0 | 0 |
| Application | 0 | 0 |
| Field activities | 0 | 0 |
| Specific practical training | 0 | 0 |
| Assignments | 1 | 20 |
| Presentation | 1 | 30 |
| Project | 0 | 0 |
| Seminar | 0 | 0 |
| Midterms | 0 | 0 |
| Final exam | 1 | 50 |
| Total | 100 | |
| Percentage of semester activities contributing grade succes | 2 | 50 |
| Percentage of final exam contributing grade succes | 1 | 50 |
| Total | 100 | |
WORKLOAD AND ECTS CALCULATION
| Activities | Number | Duration (hour) | Total Work Load |
|---|---|---|---|
| Course Duration (x14) | 14 | 3 | 42 |
| Laboratory | 0 | 0 | 0 |
| Application | 0 | 0 | 0 |
| Specific practical training | 0 | 0 | 0 |
| Field activities | 0 | 0 | 0 |
| Study Hours Out of Class (Preliminary work, reinforcement, ect) | 14 | 5 | 70 |
| Presentation / Seminar Preparation | 1 | 25 | 25 |
| Project | 0 | 0 | 0 |
| Homework assignment | 2 | 10 | 20 |
| Midterms (Study duration) | 0 | 0 | 0 |
| Final Exam (Study duration) | 1 | 20 | 20 |
| Total Workload | 32 | 63 | 177 |
Matrix Of The Course Learning Outcomes Versus Program Outcomes
| D.9. Key Learning Outcomes | Contrubition level* | ||||
|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | |
| 1. Develops and deepens their knowledge in the field of natural sciences based on the chemistry bachelor level qualifications. | X | ||||
| 2. Determines interdisciplinary interactions by analyzing information obtained from advanced scientific research. | X | ||||
| 3. Utilizes advanced theoretical and applied knowledge in their field. | X | ||||
| 4. Relates basic and advanced knowledge in their field and proposes interdisciplinary new ideas. | X | ||||
| 5. Develops scientific solution proposals and strategies using their theoretical and applied knowledge in the field. | X | ||||
| 6. Conducts individual and/or group work in research requiring expertise in their field. | X | ||||
| 7. Takes initiative to solve problems encountered in individual or group work related to their field. | X | ||||
| 8. Participates in interdisciplinary studies with their basic knowledge and analytical thinking skills. | X | ||||
| 9. Identifies lacks by monitoring scientific developments in their field and manage learning processes to conduct advanced research. | X | ||||
| 10. Accesses foreign sources in their field using at least one foreign language, updates their knowledge, and communicates with colleagues worldwide. | X | ||||
| 11. Manages data collection, interpretation, application, and dissemination processes related to their field effectively and safely while considering societal, scientific, cultural, and ethical values. | X | ||||
*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest