NNT721 - NANOPARTICULATE DRUG DELIVERY SYSTEMS
| Course Name | Code | Semester | Theory (hours/week) |
Application (hours/week) |
Credit | ECTS |
|---|---|---|---|---|---|---|
| NANOPARTICULATE DRUG DELIVERY SYSTEMS | NNT721 | Any Semester/Year | 3 | 0 | 3 | 9 |
| Prequisites | None | |||||
| Course language | Turkish | |||||
| Course type | Elective | |||||
| Mode of Delivery | Face-to-Face | |||||
| Learning and teaching strategies | Lecture Discussion | |||||
| Instructor (s) | Assist. Prof. Dr. Cem Varan | |||||
| Course objective | Providing information about preparation, characterization, stability, drug release mechanisms, administration routes, utilization, and quality control of nanoparticulate drug carrier systems | |||||
| Learning outcomes |
| |||||
| Course Content | Preparation, characterization, stability, drug release mechanisms, administration routes, utilization, and quality control of nanoparticulate drug carrier systems | |||||
| References | Lecture notes, internet. Nanoparticles for Pharmaceutical Applications, Ed: A.J. Domb, Y.Tabato, M.N.V. Ravi Kumar and S Farber. Nanoparticle Technology for Drug Delivery, Ed: Ram B. Gupta, Uday B. Kompella | |||||
Course outline weekly
| Weeks | Topics |
|---|---|
| Week 1 | Introduction of nanoparticular systems and the technological parameters effecting the formulation |
| Week 2 | Biopharmaceutical parameters effecting the formulation of nanoparticular systems |
| Week 3 | Bioavailability of nanoparticular systems |
| Week 4 | Niosome definition, preparation, advantages and disadvantages, release mechanism of active ingredient |
| Week 5 | Microemulsions, nanoemulsions, solid lipid nanospheres (SNL) and nanostructures lipid carriers (NLC): Definition, preparation, advantages and disadvantages, release mechanism of active ingredient |
| Week 6 | Liposome definition, preparation, advantages and disadvantages, release mechanism of active ingredient |
| Week 7 | Self emulsifying drug delivery systems (SEDDS) |
| Week 8 | Midterm exam |
| Week 9 | Safety and toxicology of nanoparticular drug delivery systems |
| Week 10 | Nanopspheres, nanocapsules: Definition, preparation, advantages and disadvantages, release mechanism of active ingredient |
| Week 11 | In viro characterization, quality control and stability of nanoparticular drug delivery systems |
| Week 12 | Applications and examples of nanoparticular drug delivery systems |
| Week 13 | Regulations of nanoparticular drug delivery systems |
| Week 14 | Final sınavı |
Assesment methods
| Course activities | Number | Percentage |
|---|---|---|
| Attendance | 0 | 0 |
| Laboratory | 0 | 0 |
| Application | 0 | 0 |
| Field activities | 0 | 0 |
| Specific practical training | 0 | 0 |
| Assignments | 0 | 0 |
| Presentation | 0 | 0 |
| Project | 0 | 0 |
| Seminar | 0 | 0 |
| Midterms | 1 | 50 |
| Final exam | 1 | 50 |
| Total | 100 | |
| Percentage of semester activities contributing grade succes | 0 | 50 |
| Percentage of final exam contributing grade succes | 0 | 50 |
| Total | 100 | |
WORKLOAD AND ECTS CALCULATION
| Activities | Number | Duration (hour) | Total Work Load |
|---|---|---|---|
| Course Duration (x14) | 14 | 3 | 42 |
| Laboratory | 0 | 0 | 0 |
| Application | 0 | 0 | 0 |
| Specific practical training | 0 | 0 | 0 |
| Field activities | 0 | 0 | 0 |
| Study Hours Out of Class (Preliminary work, reinforcement, ect) | 14 | 7 | 98 |
| Presentation / Seminar Preparation | 1 | 10 | 10 |
| Project | 0 | 0 | 0 |
| Homework assignment | 2 | 10 | 20 |
| Midterms (Study duration) | 1 | 50 | 50 |
| Final Exam (Study duration) | 1 | 50 | 50 |
| Total Workload | 33 | 130 | 270 |
Matrix Of The Course Learning Outcomes Versus Program Outcomes
| D.9. Key Learning Outcomes | Contrubition level* | ||||
|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | |
| 1. To be able to use mathematics, science and engineering knowledge to develop new methods in nanotechnology and nanomedicine | X | ||||
| 2. To have comprehensive information on the current techniques and methods applied in nanotechnology and nanomedicine | X | ||||
| 3. To develop methods and tools for the identification and understanding of functions and interaction mechanisms at the atomic and molecular level | X | ||||
| 4. To understand the effects of universal and social aspects in nanotechnology and nanomedicine applications. | X | ||||
| 5. To be able to use new technological developments, databases and other knowledge sources efficiently by adopting the importance of life-long learning | X | ||||
| 6. To acquire the ability of analysis, synthesis and evaluation of new ideas and developments in nanotechnology and nanomedicine | X | ||||
| 7. To have awareness of entrepreneurship and innovativeness | X | ||||
| 8. To be able to design an experiment, analyze and interpret the experimental results as a written report. | X | ||||
| 9. An ability to perform disciplinary and interdisciplinary team work | X | ||||
| 10. An ability to present the results of the studies orally or written in national and international platforms and contribute to the scientific literature. | X | ||||
| 11. To have consciousness about professional ethics and social responsibility | X | ||||
*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest