BÄ°K725 - BIOCHEMISTRY of IMMUNE SYSTEM

Course Name Code Semester Theory
(hours/week)
Application
(hours/week)
Credit ECTS
BIOCHEMISTRY of IMMUNE SYSTEM BÄ°K725 Any Semester/Year 3 0 3 9
PrequisitesNone
Course languageTurkish
Course typeElective 
Mode of DeliveryFace-to-Face 
Learning and teaching strategiesLecture
Other: presentation  
Instructor (s)Prof.Dr. Gülberk Uçar, Assoc.Prof.Dr. AyÅŸe Ercan 
Course objectiveTo review the basic biochemical aspects of immunology and the disorders of the immune system. 
Learning outcomes
  1. At the end of the course, the students should describe the components of the immune system and should be knowledged about the fundamentals of innate and adaptive mechanisms of immunity; the mechanisms of complement activation; regulation and genetic control of immunity, and immunological tolerance.
Course ContentInnate and acquired immunity; cells involved in the immune response, the lymphoid system, molecules which recognize antigen, cell mediated immune response; regulation and genetic control of immunity, immunological tolerance. 
References1. Stites,D.P. Medical Immunology, Prentice Hall Int. Inc., London, 1997.
2. Abbas, A.K. Cellular and Molecular Immunology, W.B.Saunders Company, USA, 2000.
3. Janeway CA. Immunobiology 6: The Immune System in Health and Disease, 6th Edition, Garland Publishing, 2005.
4. Kuby, J., Immunology, W.H.Freeman, USA, 1997
5. Roitt et al, Immunology, 5th edition, Mosby Publishing, 1998.
 

Course outline weekly

WeeksTopics
Week 1Innate and acquired immunity; cells involved in the immune response, the lymphoid system
Week 2Antigens;Structures and functions of the immunoglobulins
Week 3Antigen-immunoglobulin interaction
Week 4Maturation and the diversity of B cells
Week 5MHC & Generating Immune Diversity
Week 6Processing and presentation of antigen
Week 7T cell receptor; maturation and diversity of T cells
Week 8Cytokines
Week 9Midterm exam
Week 10Complement system
Week 11The inflammatory Response
Week 12Cell-mediated Immunity
Week 13Vaccination
Week 14Autoimmunity
Week 15Immunodeficiency disorders
Week 16Final exam

Assesment methods

Course activitiesNumberPercentage
Attendance00
Laboratory00
Application00
Field activities00
Specific practical training00
Assignments00
Presentation00
Project00
Seminar00
Midterms150
Final exam150
Total100
Percentage of semester activities contributing grade succes150
Percentage of final exam contributing grade succes150
Total100

WORKLOAD AND ECTS CALCULATION

Activities Number Duration (hour) Total Work Load
Course Duration (x14) 14 3 42
Laboratory 0 0 0
Application000
Specific practical training000
Field activities000
Study Hours Out of Class (Preliminary work, reinforcement, ect)16464
Presentation / Seminar Preparation000
Project000
Homework assignment11444
Midterms (Study duration)51050
Final Exam (Study duration) 71070
Total Workload5331270

Matrix Of The Course Learning Outcomes Versus Program Outcomes

D.9. Key Learning OutcomesContrubition level*
12345
1. The student has advanced theoretical and practical knowledge on biochemistry and enhances this knowledge. X   
2. Knows professional ethics (intellectual property, academic integrity, ethics in human relations: avoids discrimination, values merit, respects privacy etc), research and publication ethics and applies this information.X    
3. Reviews and analyzes the recent literature on a specific subject, formulates a unique hypothesis from this analysis and writes a project on this subject.      
4. Has advanced knowledge on the uses of instruments and methods specific to the field of biochemistry as well as other technological equipment including computers and uses them in the course of projects.      
5. Independently can head a project-based scientific work from start to finish, finalize the work, analyze the data through relevant statistical methods and contributes to progress in the field.      
6. Follows evidence based applications, does research and contributes to produce knowledge which can be put to good use in society. X   
7. Writes the report of the research participated in or made by self and contributes to universal knowledge by publishing it in a peer-reviewed journal and presenting it at scientific meetings.      
8. Can formulate alternative solutions to scientific problems in the field and critically analyze and evaluate new information.      
9. Takes part in national and international multi-disciplinary studies both as leader or participant and through effective communication can relay distinctive ideas in scientific discussions and provides feed-back.      
10. Can independently manage a research laboratory and has managing and teaching skills for making strategic decisions.      
11. Is open to renovation and in continuous self development. X    
12. Even without any previous experience, can structure and apply a method on if needed.     
13. Is in command of native language, can communicate at an advanced level using written, oral and visual techniques and debates. X    
14. Has proficiency in English both to follow the advances in the field and to contribute to it using written, oral and visual techniques.  X   

*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest