EFT626 - OCULAR DRUG DELIVERY SYSTEMS II

Course Name Code Semester Theory
(hours/week)
Application
(hours/week)
Credit ECTS
OCULAR DRUG DELIVERY SYSTEMS II EFT626 Any Semester/Year 3 0 3 7
Prequisites
Course languageTurkish
Course typeElective 
Mode of DeliveryFace-to-Face 
Learning and teaching strategiesLecture
Discussion
Preparing and/or Presenting Reports
 
Instructor (s)Prof. Dr. Sibel Pehlivan, Asst. Prof. Eren Aytekin 
Course objectiveTo evaluate ocular drug delivery from a biopharmaceutical aspect. 
Learning outcomes
  1. The students will gain information on ocular drug delivery systems.
Course ContentA summary of content for this course is as follows: factors affecting the release and permeation of drugs through the ocular membranes after the administration of different ocular dosage forms; influence of site of administration, patients status and characteristics of diseases, preparation method of the delivery system, way of administration, dose applied and frequency of dose are the examples of these above factors.  
References1. Newel, F.W., Ophthalmology principles and concepts. 6th Edition, St. Lours, Toronto, Princeton: The C.V. Mosby Company, 582, 1986.
2. Reddy, I.K., Ganesan, M.G., Ocular therapeutics and drug delivery: an overview. ?Ocular Therapeutics and Drug Delivery. (Ed.I.K. Reddy), Technomic Publishing Co. Inc., Lancaster-Basel, s. 3-23, 1996.
3. Maurice, D.M., Mishima, S., Ocular pharmacokinetics. ?Ocular Pharmacokinetics in Pharmacology of the Eye (Ed. M.L. Sears), Spinger-Verlag Berlin Heidelberg New York Tokyo, s.19-116, 1984. 

Course outline weekly

WeeksTopics
Week 1Definitions
Week 2Anatomy and physiology of eye
Week 3Ophthalmic microparticulate systems
Week 4Ophthalmic microparticles and nanoparticles
Week 5Semi solid dosage forms administered to eyes
Week 6Solid dosage forms which are applied to eyes
Week 7Ocular inserts, lenses and tablets
Week 8Ocular pumps
Week 9Ocular implants
Week 10Dry eye syndrome and artificial tear formulation
Week 11Methods used for increasing ocular drug permeation through the ocular membrane
Week 12Midterm assignment and presentation
Week 13The methods which are used for increase the ocular drug permeation through the ocular membrane
Week 14Discussion
Week 15Preparation for the final exam
Week 16Final exam

Assesment methods

Course activitiesNumberPercentage
Attendance00
Laboratory00
Application00
Field activities00
Specific practical training00
Assignments00
Presentation150
Project00
Seminar00
Midterms00
Final exam150
Total100
Percentage of semester activities contributing grade succes150
Percentage of final exam contributing grade succes150
Total100

WORKLOAD AND ECTS CALCULATION

Activities Number Duration (hour) Total Work Load
Course Duration (x14) 14 3 42
Laboratory 0 0 0
Application000
Specific practical training000
Field activities000
Study Hours Out of Class (Preliminary work, reinforcement, ect)14456
Presentation / Seminar Preparation15252
Project000
Homework assignment000
Midterms (Study duration)000
Final Exam (Study duration) 16060
Total Workload30119210

Matrix Of The Course Learning Outcomes Versus Program Outcomes

D.9. Key Learning OutcomesContrubition level*
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*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest