EFT614 - BIODEGRADABLE POLYMERS IN DRUG DELIVERY SYSTEMS
Course Name | Code | Semester | Theory (hours/week) |
Application (hours/week) |
Credit | ECTS |
---|---|---|---|---|---|---|
BIODEGRADABLE POLYMERS IN DRUG DELIVERY SYSTEMS | EFT614 | Any Semester/Year | 3 | 0 | 3 | 7 |
Prequisites | ||||||
Course language | Turkish | |||||
Course type | Elective | |||||
Mode of Delivery | Face-to-Face | |||||
Learning and teaching strategies | Lecture Discussion Preparing and/or Presenting Reports | |||||
Instructor (s) | Prof. Sema Çalış | |||||
Course objective | The aim can be stated as to teach the general properties of biopolymers and rationale for designing and preparing dosage forms for drug delivery using these polymers. | |||||
Learning outcomes |
| |||||
Course Content | In the cover of this course, the importance of biodegradable polymers from formulation aspect of pharmaceutical technology is emphasized, related terminology is defined and after a classification of biopolymers, basic knowledge concerning natural and synthetic properties of biopolymers are presented. Properties of Poly(lactide-co-glycolide) (PLGA) polymers, design and development of drug delivery system using this FDA approved biodegradable, biocompatible and synthetic polymer is also discussed in detail using update literature. | |||||
References | 1. Peptide and Protein Drug Delivery, Ed. Vincent H. L. Lee, 1991, Marcel Dekker, Inc., New York-USA. 2. Formulation, Characterisation and Stability of Protein Drugs, Eds. Rodney Pearlman, Y. John Wang, 1996, Plenum Press, New York-USA. 3. Physical Methods to Characterize Pharmaceutical Proteins, Eds. James N. Herran, Wim Jiskot, Daan J. A. Crommelin, 1995, Plenum Press, New York-USA. |
Course outline weekly
Weeks | Topics |
---|---|
Week 1 | Introduction to polymers, definitions of homopolymers, copolymers and graft polymers |
Week 2 | Classification of polymers and examples of polymer types |
Week 3 | Introduction to biodegradable polymers |
Week 4 | Explanations on related terminology of biodegradable polymers; biodegradation, bioresorption, bioabsorption, bioerosion and biodeteroriation |
Week 5 | Introduction to general properties of poly (lactide-co-glycolide)(PLGA) |
Week 6 | Synthesis of PLGA polymers, biodegradation, polymer characteristics |
Week 7 | Polymer degradation and erosion mechanism |
Week 8 | Discussion on current literature |
Week 9 | Sterilization approaches for PLGA including formulations |
Week 10 | Design of microparticulate systems prepared by PLGA polymers |
Week 11 | Introduction to natural biodegradable polymers and general properties |
Week 12 | Design of drug delivery systems using natural biodegradable polymers |
Week 13 | Biomedical applications of polymeric materials |
Week 14 | Current status of biodegradable polymers, evaluation of technological significance and future expectations |
Week 15 | Preparation for the Final Exam |
Week 16 | Final exam |
Assesment methods
Course activities | Number | Percentage |
---|---|---|
Attendance | 0 | 0 |
Laboratory | 0 | 0 |
Application | 0 | 0 |
Field activities | 0 | 0 |
Specific practical training | 0 | 0 |
Assignments | 0 | 0 |
Presentation | 1 | 25 |
Project | 0 | 0 |
Seminar | 0 | 0 |
Midterms | 1 | 25 |
Final exam | 1 | 50 |
Total | 100 | |
Percentage of semester activities contributing grade succes | 2 | 50 |
Percentage of final exam contributing grade succes | 1 | 50 |
Total | 100 |
WORKLOAD AND ECTS CALCULATION
Activities | Number | Duration (hour) | Total Work Load |
---|---|---|---|
Course Duration (x14) | 14 | 3 | 42 |
Laboratory | 0 | 0 | 0 |
Application | 0 | 0 | 0 |
Specific practical training | 0 | 0 | 0 |
Field activities | 0 | 0 | 0 |
Study Hours Out of Class (Preliminary work, reinforcement, ect) | 14 | 4 | 56 |
Presentation / Seminar Preparation | 1 | 16 | 16 |
Project | 0 | 0 | 0 |
Homework assignment | 0 | 0 | 0 |
Midterms (Study duration) | 1 | 36 | 36 |
Final Exam (Study duration) | 1 | 60 | 60 |
Total Workload | 31 | 119 | 210 |
Matrix Of The Course Learning Outcomes Versus Program Outcomes
D.9. Key Learning Outcomes | Contrubition level* | ||||
---|---|---|---|---|---|
1 | 2 | 3 | 4 | 5 |
*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest