MEB721 - GENETIC INFORMATION FLOW
| Course Name | Code | Semester | Theory (hours/week) |
Application (hours/week) |
Credit | ECTS |
|---|---|---|---|---|---|---|
| GENETIC INFORMATION FLOW | MEB721 | 2nd Semester | 3 | 0 | 3 | 7 |
| Prequisites | Limited to a quota of 10 students | |||||
| Course language | Turkish | |||||
| Course type | Elective | |||||
| Mode of Delivery | Face-to-Face | |||||
| Learning and teaching strategies | Lecture Discussion Question and Answer Team/Group Work | |||||
| Instructor (s) | Prof. Hayat YURTER | |||||
| Course objective | The objective of this course is to gain knowledge about gene expression and regulation and to follow related current literature in the field of molecular genetics. | |||||
| Learning outcomes |
| |||||
| Course Content | In this course; the flow of genetic information, RNA classes, mechanism and regulation of transcription/ translation will be discussed in detail. | |||||
| References | 1. Molecular Biology of the Cell ed. B. Alberts et.al. 2002 Garland Science. 2. Concepts of genetics W.S. Klug, 1994 MacMillan. 3. Genes and genomes, M. Singer, 1991, Blackwell. 4. Genomes, T.A. Brown, 1999, Bios Scientific. 5. Related current literature. | |||||
Course outline weekly
| Weeks | Topics |
|---|---|
| Week 1 | The genetic code, the flow of information, central dogma |
| Week 2 | The transcription of class I, II and III genes |
| Week 3 | Article discussion (Presentation) |
| Week 4 | The regulation of transcription |
| Week 5 | Article discussion (Presentation) |
| Week 6 | The structure, the classes and the features of RNA |
| Week 7 | Article discussion (Presentation) |
| Week 8 | RNA processing: capping, polyadenilation, splicing, chemical modifications |
| Week 9 | Article discussion (Presentation) |
| Week 10 | Prokaryotic and eukaryotik protein synthesis (ribosome, aminoacyl synthetase, antibiotics) |
| Week 11 | The regulation of translation and formation of functional proteins |
| Week 12 | Article discussion (Presentation) |
| Week 13 | The regulation of the gene activity, the transient and permanent changes in the genome activity. |
| Week 14 | Homework assignment |
| Week 15 | Preparation for the final exam |
| Week 16 | Final exam |
Assesment methods
| Course activities | Number | Percentage |
|---|---|---|
| Attendance | 0 | 0 |
| Laboratory | 0 | 0 |
| Application | 0 | 0 |
| Field activities | 0 | 0 |
| Specific practical training | 0 | 0 |
| Assignments | 1 | 10 |
| Presentation | 5 | 30 |
| Project | 0 | 0 |
| Seminar | 0 | 0 |
| Midterms | 0 | 0 |
| Final exam | 1 | 60 |
| Total | 100 | |
| Percentage of semester activities contributing grade succes | 6 | 40 |
| Percentage of final exam contributing grade succes | 1 | 60 |
| Total | 100 | |
WORKLOAD AND ECTS CALCULATION
| Activities | Number | Duration (hour) | Total Work Load |
|---|---|---|---|
| Course Duration (x14) | 14 | 3 | 42 |
| Laboratory | 0 | 0 | 0 |
| Application | 0 | 0 | 0 |
| Specific practical training | 0 | 0 | 0 |
| Field activities | 0 | 0 | 0 |
| Study Hours Out of Class (Preliminary work, reinforcement, ect) | 14 | 6 | 84 |
| Presentation / Seminar Preparation | 5 | 10 | 50 |
| Project | 0 | 0 | 0 |
| Homework assignment | 1 | 10 | 10 |
| Midterms (Study duration) | 0 | 0 | 0 |
| Final Exam (Study duration) | 1 | 15 | 15 |
| Total Workload | 35 | 44 | 201 |
Matrix Of The Course Learning Outcomes Versus Program Outcomes
| D.9. Key Learning Outcomes | Contrubition level* | ||||
|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | |
| 1. Learn and process the information in the field of cell biology at an academic level (KNOWLEDGE). | |||||
| 2. Learn and process the information in the field of molecular biology and genetics at an academic level (KNOWLEDGE). | X | ||||
| 3. Learn and process the information in the field of inheritance at an academic level (KNOWLEDGE). | |||||
| 4. Learn and process the information in the field of genomics and functional genomics at an academic level (KNOWLEDGE). | X | ||||
| 5. Have theoretical/ practical skills for preparing and carrying out an independent research project (SKILLS). | |||||
| 6. Follow and discuss national/international publications (SKILLS). | |||||
| 7. Apply ethical and legal rules at the institutional, national and international level (SKILLS). | |||||
| 8. Design and implement studies efficiently related to genomics technologies (SKILLS). | |||||
| 9. Use information technologies and bioinformatics tools effectively (SKILLS). | |||||
| 10. Take responsibility in a team and/or carry out independent research (QUALIFICATION). | |||||
| 11. Gain critical thinking and solve scientific problems in accordance with ethical reflection (QUALIFICATION). | |||||
| 12. Prepare scientific publications for national/international-refereed journals (QUALIFICATION). | |||||
| 13. Apply biosafety rules and follow good laboratory practices (QUALIFICATION). | |||||
| 14. Have competence in setting up a new laboratory infrastructure in the field of genomics and manage a working team (QUALIFICATION). | |||||
| 15. Make scientific presentations at the national/international meetings (QUALIFICATION). | |||||
*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest