BÄ°K716 - MEMBRANE RECEPTORS
| Course Name | Code | Semester | Theory (hours/week) |
Application (hours/week) |
Credit | ECTS |
|---|---|---|---|---|---|---|
| MEMBRANE RECEPTORS | BÄ°K716 | Any Semester/Year | 3 | 0 | 3 | 9 |
| Prequisites | ||||||
| Course language | Turkish | |||||
| Course type | Elective | |||||
| Mode of Delivery | Face-to-Face | |||||
| Learning and teaching strategies | Other: Lectures with active student participation | |||||
| Instructor (s) | Prof.Dr.A. Kevser Özden | |||||
| Course objective | To explain membrane structure with relevance to membrane receptors. To classify membrane receptors based on their signal trunsduction pathways. To teach basic signal pathways and their interactions. To follow the new advances in the field. | |||||
| Learning outcomes |
| |||||
| Course Content | Structural and dynamic properties of plasma membrane, general and kinetic properties of membrane receptors, G proteins and G coupled receptors, lipids and signal trunsduction, receptors with enzyme activity, clinical and pharmacological importance of membrane receptors and signal trunsduction. | |||||
| References | 1. The Cell: A molecular Approach (2009), G. Cooper, R.E. Hausman, 5th ed., ASM Press, Washington DC. 2. Molecular Biology of the Cell, B. Alberts, A. Johnson, et. al., 5th ed., Garland Publ. Inc., New York 3. Relevant current articles | |||||
Course outline weekly
| Weeks | Topics |
|---|---|
| Week 1 | Introduction to membrane receptors and signal trunsduction |
| Week 2 | Structural features of cell membrane |
| Week 3 | Membrane transport and vesicular transport |
| Week 4 | General properties of membrane receptors |
| Week 5 | Receptor kinetics |
| Week 6 | Ä°ntroduction to signal trunsduction:Phosphorylation, calcium-calmodulin |
| Week 7 | Paper presentation |
| Week 8 | G proteins |
| Week 9 | Cyclic nucleotides |
| Week 10 | Channel receptors |
| Week 11 | Receptors with enzymatic activity |
| Week 12 | Paper presentation |
| Week 13 | Interactions between signal trunsduction pathways |
| Week 14 | Clinical and pharmacological importance of membrane receptors and signal trunsduction |
| Week 15 | Preparation for the exam |
| Week 16 | FINAL EXAMINATION |
Assesment methods
| Course activities | Number | Percentage |
|---|---|---|
| Attendance | 14 | 10 |
| Laboratory | 0 | 0 |
| Application | 0 | 0 |
| Field activities | 0 | 0 |
| Specific practical training | 0 | 0 |
| Assignments | 0 | 0 |
| Presentation | 2 | 40 |
| Project | 0 | 0 |
| Seminar | 0 | 0 |
| Midterms | 0 | 0 |
| Final exam | 1 | 50 |
| Total | 100 | |
| Percentage of semester activities contributing grade succes | 16 | 50 |
| Percentage of final exam contributing grade succes | 1 | 50 |
| Total | 100 | |
WORKLOAD AND ECTS CALCULATION
| Activities | Number | Duration (hour) | Total Work Load |
|---|---|---|---|
| Course Duration (x14) | 14 | 3 | 42 |
| Laboratory | 0 | 0 | 0 |
| Application | 0 | 0 | 0 |
| Specific practical training | 0 | 0 | 0 |
| Field activities | 0 | 0 | 0 |
| Study Hours Out of Class (Preliminary work, reinforcement, ect) | 10 | 5 | 50 |
| Presentation / Seminar Preparation | 2 | 24 | 48 |
| Project | 0 | 0 | 0 |
| Homework assignment | 8 | 12 | 96 |
| Midterms (Study duration) | 0 | 0 | 0 |
| Final Exam (Study duration) | 1 | 34 | 34 |
| Total Workload | 35 | 78 | 270 |
Matrix Of The Course Learning Outcomes Versus Program Outcomes
| D.9. Key Learning Outcomes | Contrubition level* | ||||
|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | |
| 1. The student has advanced theoretical and practical knowledge on biochemistry and enhances this knowledge. | X | ||||
| 2. Knows professional ethics (intellectual property, academic integrity, ethics in human relations: avoids discrimination, values merit, respects privacy etc), research and publication ethics and applies this information. | |||||
| 3. Reviews and analyzes the recent literature on a specific subject, formulates a unique hypothesis from this analysis and writes a project on this subject. | |||||
| 4. Has advanced knowledge on the uses of instruments and methods specific to the field of biochemistry as well as other technological equipment including computers and uses them in the course of projects. | |||||
| 5. Independently can head a project-based scientific work from start to finish, finalize the work, analyze the data through relevant statistical methods and contributes to progress in the field. | |||||
| 6. Follows evidence based applications, does research and contributes to produce knowledge which can be put to good use in society. | |||||
| 7. Writes the report of the research participated in or made by self and contributes to universal knowledge by publishing it in a peer-reviewed journal and presenting it at scientific meetings. | |||||
| 8. Can formulate alternative solutions to scientific problems in the field and critically analyze and evaluate new information. | |||||
| 9. Takes part in national and international multi-disciplinary studies both as leader or participant and through effective communication can relay distinctive ideas in scientific discussions and provides feed-back. | |||||
| 10. Can independently manage a research laboratory and has managing and teaching skills for making strategic decisions. | |||||
| 11. Is open to renovation and in continuous self development. | |||||
| 12. Even without any previous experience, can structure and apply a method on if needed. | |||||
| 13. Is in command of native language, can communicate at an advanced level using written, oral and visual techniques and debates. | |||||
| 14. Has proficiency in English both to follow the advances in the field and to contribute to it using written, oral and visual techniques. | |||||
*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest