BÄ°K604 - BASIC BIOCHEMISTRY: METABOLISM

Course Name Code Semester Theory
(hours/week)
Application
(hours/week)
Credit ECTS
BASIC BIOCHEMISTRY: METABOLISM BÄ°K604 Any Semester/Year 4 0 4 8
PrequisitesBÄ°K603
Course languageTurkish
Course typeElective 
Mode of DeliveryFace-to-Face 
Learning and teaching strategiesLecture
Discussion
 
Instructor (s)Prof.Dr. Asuman Özkara 
Course objectiveTo appreciate metabolic integration through learning main metabolic pathways and their control mechanisms in living organisms. 
Learning outcomes
  1. 1. Describes the synthetic and degradative pathways and their control mechanisms in carbohydrate, lipid, amino acid and nucleotide metabolisms.
  2. 2. Explains the information transfer in the cell through RNA and protein metabolisms, and control of gene expression.
  3. 3. Describes the hormonal control of metabolism and its integration at the whole organism level.
  4. 4. Describes how energy is produced in a living organism and explain the functioning of metabolism based on bioenergetic principles.
Course ContentCarbohydrate, lipid, amino acid and nucleotide metabolisms; photosynthesis; ATP synthesis via electron transport chain and oxidative phosphorylation; RNA and protein metabolisms; control of gene expression; hormonal regulation and integration of metabolism. 
ReferencesLehninger Principles of Biochemistry, 6. baskı
Nelson DL, Cox MM (editörler), 2017, WH Freeman and Company, New York 

Course outline weekly

WeeksTopics
Week 1Glycolysis, gluconeogenesis, glycogen metabolism
Week 2Citric acid cyle
Week 3Pentose phosphate and uronic acid pathways, photosynthesis
Week 4Fatty acid catabolism
Week 5Biosynthesis of lipids
Week 6Amino acid oxidation and the production of urea
Week 7Biosynthesis of amino acids and related compounds
Week 8Midterm exam
Week 9Electron transport chain and oxidative phosphorylation
Week 10Nucleotide metabolism
Week 11Hormonal regulation and integration of metabolism
Week 12Transcription and RNA processing
Week 13Translation, protein targeting and turnover
Week 14Regulation of gene expression
Week 15Preparation to final examination
Week 16Final exam

Assesment methods

Course activitiesNumberPercentage
Attendance00
Laboratory00
Application00
Field activities00
Specific practical training00
Assignments00
Presentation00
Project00
Seminar00
Midterms150
Final exam150
Total100
Percentage of semester activities contributing grade succes050
Percentage of final exam contributing grade succes050
Total100

WORKLOAD AND ECTS CALCULATION

Activities Number Duration (hour) Total Work Load
Course Duration (x14) 14 4 56
Laboratory 0 0 0
Application000
Specific practical training000
Field activities000
Study Hours Out of Class (Preliminary work, reinforcement, ect)1411154
Presentation / Seminar Preparation000
Project000
Homework assignment000
Midterms (Study duration)11515
Final Exam (Study duration) 11515
Total Workload3045240

Matrix Of The Course Learning Outcomes Versus Program Outcomes

D.9. Key Learning OutcomesContrubition level*
12345
1. Students will be able to follow the conceptual and scientific developments related to basic measurement and evaluation techniques specific to the Exercise and Sports Physiology, and use the deep and systematic knowledge specific to the field of Exercise and Sports Physiology in their professional and academic studies.  X  
2. Has the laboratory safety and technical knowledge and skills required for laboratory studies in Exercise and Sport Physiology, and able to solve the research problems using the tools and equipment in the field. X   
3. Has the competency to analyse and integrate the information from other disciplines, synthesize new information, make decisions and solve problems by using theoretical and applied concepts and principles in Exercise and Sport Physiology with a critical approach. X   
4. Has the competency to conduct research, take part in research projects, chose the appropriate statistical methods, interpret the results of his/her work, write the report and present it in scientific meetings or publish.  X  
5. Evaluates national/international strategies, politics and practices related to Exercise and Sports Physiology in line with the national values and country realities.  X  
6. Acts in compliance with legislation, professional values and ethical principles in the formation of knowledge related to Exercise and Sports Physiology, and transfers his/her professional knowledge, skills and responsibilities to team work.  X  
7. Reads and analyses the scientific papers in Exercise and Sports Physiology, conducts and carries out evidenced based research in the concerned professional field. X   
8. Knows the importance of communication with other sciences related to Exercise and Sport Physiology, uses his/her knowledge and problem solving abilities in interdisciplinary studies.   X 
9. Adopts lifelong learning principles, identifies his/her learning needs and goals, and contributes to quality improvement, vocational training and promotion programs in Exercise and Sports Physiology.   X 
10. Establishes written, verbal and visual communication with national and international scientists and defends his/her opinions on the issues in Exercise and Sports Physiology.  X  

*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest