MEB618 - MOLECULAR GENETICS

Course Name Code Semester Theory
(hours/week)		 Application
(hours/week)		 Credit ECTS
MOLECULAR GENETICS MEB618 2nd Semester 3 0 3 7
PrequisitesLimited to a quota of 10 students.
Course languageTurkish
Course typeElective 
Mode of DeliveryFace-to-Face 
Learning and teaching strategiesLecture
Discussion
Team/Group Work
 
Instructor (s)Prof. Serap Dökmeci 
Course objectiveStructure, function, regulation and organization of the genetic material at the molecular level 
Learning outcomes
  1. Students will remember and use the basic knowledge about the genetic material in the cell.
  2. Students will remember and explain the relationship between molecules which take part in genetic information flow.
  3. Students will use the knowledge about gene expression and regulation.
  4. Students will be aware of latest articles about molecular genetic field.
Course ContentIn this course, general properties of nucleic acids and prokaryotic/eukaryotic cell genome, genetic information flow and regulation topics will be discussed. 
References1. Alberts: Molecular Biology of The Cell 5th Edition, 2008.
2. Genomes 3, 3rd Edition by T.A. Brown, 2006.
3. Related published articles.
 

Course outline weekly

WeeksTopics
Week 1DNA: Structure and function
Week 2DNA replication
Week 3Chromatin structure
Week 4RNA structure and function
Week 5Genetic information flow: RNA synthesis
Week 6RNA processing
Week 7Presentations and group discussion
Week 8Genetic information flow: Protein synthesis
Week 9Protein modifications
Week 10Control of gene expression in prokaryotes
Week 11Control of gene expression in eukaryotes
Week 12Eukaryotic genome organization
Week 13Eukaryotic genome organization
Week 14Homework assignment
Week 15Preparation to final exam
Week 16Final exam

Assesment methods

Course activitiesNumberPercentage
Attendance00
Laboratory00
Application00
Field activities00
Specific practical training00
Assignments110
Presentation120
Project00
Seminar00
Midterms00
Final exam170
Total100
Percentage of semester activities contributing grade succes230
Percentage of final exam contributing grade succes170
Total100

WORKLOAD AND ECTS CALCULATION

Activities Number Duration (hour) Total Work Load
Course Duration (x14) 14 3 42
Laboratory 0 0 0
Application000
Specific practical training000
Field activities000
Study Hours Out of Class (Preliminary work, reinforcement, ect)149126
Presentation / Seminar Preparation11414
Project000
Homework assignment11414
Midterms (Study duration)000
Final Exam (Study duration) 11515
Total Workload3155211

Matrix Of The Course Learning Outcomes Versus Program Outcomes

D.9. Key Learning OutcomesContrubition level*
12345
1. Accesses medical literature on basic and clinical immunology and -related fields and evaluates them.    X 
2. Gains the necessary theoretical knowledge for their research and formulates hypotheses. Conducts research on immune system components and molecular structures, plans the appropriate methodology.    X 
3. Investigates gene structures from molecular literature studies, demonstrates them through sequence analysis, interprets the data, reaches conclusions, and publishes these findings.    X 
4. Demonstrates comprehensive and systematic knowledge on basic immunology, including understanding immunological mechanisms, immune system components, and their functions, also possesses knowledge in molecular genetics and biology.    X 
5. Utilizes current statistical approach to evaluate the obtained data. Presents research at national and international conferences and publishes findings under mentorship.    X 
6. Upon completion of the basic immunology master's program, the student, under the guidance of their consultant, drafts a research proposal adhering to ethical guidelines, determines the budget, provides feedback on projects authored by other researchers, participates in collaborative projects from the planning stage, offers insights, suggests changes, and presents alternative solutions.   X 

*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest