ERF611 - RADIOPHARMACEUTICALS
| Course Name | Code | Semester | Theory (hours/week) |
Application (hours/week) |
Credit | ECTS |
|---|---|---|---|---|---|---|
| RADIOPHARMACEUTICALS | ERF611 | Any Semester/Year | 2 | 0 | 2 | 7 |
| Prequisites | ||||||
| Course language | Turkish | |||||
| Course type | Elective | |||||
| Mode of Delivery | Face-to-Face | |||||
| Learning and teaching strategies | Lecture Discussion | |||||
| Instructor (s) | Prof. Dr. Suna Erdoğan, Dr.Öğr.Üyesi Mine Silindir Günay | |||||
| Course objective | The course aim is to introduce the student radionuclide production, the radiopharmaceuticals in pharmacopoeia and to teach their usage in clinics. | |||||
| Learning outcomes |
| |||||
| Course Content | - Terminology - Principles of radiopharmaceuticals - Officinal and new radiopharmaceuticals; quality control, industrial production, design of new radiopharmaceuticals - Tc-99m radiopharmaceuticals - Radioiodinated radiopharmaceuticals - PET radiopharmaceuticals - Radiopharmaceuticals labeled with other radionuclides - Parameters effecting the usage of radiopharmaceuticals | |||||
| References | 1- A Theobald, Radiopharmaceuticals: Using Radioactive Compounds in Pharmaceutics and Medicine, Taylor & Francis, 1989. 2- GA Andrews, RM Kniseley, HN Wagner, Radioactive Pharmaceuticals, 1966. 3- Gopal B. Saha, Fundamentals of Nuclear Pharmacy, New York, Springer, 2004. 4- IAEA TEC DOC , Production of 99mTc-Radiopharmaceuticals for Brain, Heart, Kidney Imaging, 1995. 5- IAEA TEC DOC 649, Preparation Kits for 99mTc Radiopharmaceuticals, 1992. | |||||
Course outline weekly
| Weeks | Topics |
|---|---|
| Week 1 | Introduction and terminology |
| Week 2 | Principles in radiopharmaceuticals |
| Week 3 | Officinal and new radiopharmaceuticals; quality control, industrial production |
| Week 4 | Officinal and new radiopharmaceuticals; Tc-99m Radiopharmaceuticals |
| Week 5 | Officinal and new radiopharmaceuticals; Tc-99m Radiopharmaceuticals (cont) |
| Week 6 | Midterm exam |
| Week 7 | Officinal and new radiopharmaceuticals; radioiodinated radiopharmaceuticals |
| Week 8 | Officinal and new radiopharmaceuticals; radioiodinated radiopharmaceuticals (cont) |
| Week 9 | Officinal and new radiopharmaceuticals; PET radiopharmaceuticals |
| Week 10 | Officinal and new radiopharmaceuticals; radiopharmaceuticals labeled with other radionuclides |
| Week 11 | Officinal and new radiopharmaceuticals; radiopharmaceuticals labeled with other radionuclides (cont) |
| Week 12 | Design of new radiopharmaceuticals |
| Week 13 | Design of new radiopharmaceuticals (cont) |
| Week 14 | Parameters effecting the usage of radiopharmaceuticals (cont) |
| Week 15 | Arrangements for final exam |
| Week 16 | Final exam |
Assesment methods
| Course activities | Number | Percentage |
|---|---|---|
| Attendance | 0 | 0 |
| Laboratory | 0 | 0 |
| Application | 0 | 0 |
| Field activities | 0 | 0 |
| Specific practical training | 0 | 0 |
| Assignments | 0 | 0 |
| Presentation | 0 | 0 |
| Project | 0 | 0 |
| Seminar | 0 | 0 |
| Midterms | 1 | 50 |
| Final exam | 1 | 50 |
| Total | 100 | |
| Percentage of semester activities contributing grade succes | 1 | 50 |
| Percentage of final exam contributing grade succes | 1 | 50 |
| Total | 100 | |
WORKLOAD AND ECTS CALCULATION
| Activities | Number | Duration (hour) | Total Work Load |
|---|---|---|---|
| Course Duration (x14) | 14 | 2 | 28 |
| Laboratory | 0 | 0 | 0 |
| Application | 0 | 0 | 0 |
| Specific practical training | 0 | 0 | 0 |
| Field activities | 0 | 0 | 0 |
| Study Hours Out of Class (Preliminary work, reinforcement, ect) | 14 | 2 | 28 |
| Presentation / Seminar Preparation | 0 | 0 | 0 |
| Project | 0 | 0 | 0 |
| Homework assignment | 0 | 0 | 0 |
| Midterms (Study duration) | 1 | 64 | 64 |
| Final Exam (Study duration) | 1 | 90 | 90 |
| Total Workload | 30 | 158 | 210 |
Matrix Of The Course Learning Outcomes Versus Program Outcomes
| D.9. Key Learning Outcomes | Contrubition level* | ||||
|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | |
| 1. Searches current information in his field. Knows how to conduct scientific research and access information sources, and evaluates and uses this information. | |||||
| 2. Designs, carries out and evaluates scientific studies using theoretical and practical knowledge at the level of expertise acquired in that field. | X | ||||
| 3. Performs statistical analysis and interpretation of data obtained from studies. | |||||
| 4. Presents the results obtained from scientific studies in scientific meetings, prepare the reports of results and publishes the results of studies in national and/or international journal. | |||||
| 5. Has the theoretical knowledge and appropriate skills on formulation, manufacturing, stability, quality assurance, regulatory affairs, and other regulations and distributions of radiopharmaceuticals. | X | ||||
| 6. Has the knowledge on effect of radiation on pharmaceutics, cosmetics and their raw materilas, drug delivery systems and medical devices and know how to control and/or prevent the possible changes occured by gamma irradiation. | |||||
| 7. Knows the biological effect of ionized radiation. Follow the rules required for radiation protection to protect the radiation worker, public and environment. | |||||
| 8. Applies the principles of GMP and GRP in whole process of life cycle of radiopharmacuticals. | |||||
| 9. Applies principles of professional development and lifelong learning, communication and social skills on professional practices. | |||||
*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest