TÄ°M601 - BASIC IMMUNOLOGY I

Course Name Code Semester Theory
(hours/week)		 Application
(hours/week)		 Credit ECTS
BASIC IMMUNOLOGY I TÄ°M601 1st Semester 3 0 3 7
Prequisitesnone
Course languageTurkish
Course typeMust 
Mode of DeliveryFace-to-Face 
Learning and teaching strategiesLecture
Discussion
Question and Answer
Preparing and/or Presenting Reports
 
Instructor (s)Prof. Dr. GüneÅŸ EsendaÄŸlı, Doç. Dr. Hande Canpınar, Doç.Dr. Gürcan Günaydın, Doç.Dr. Begüm Kocatürk 
Course objectiveTo learn the principal properties and mechanisms of the immune system. Every student is in charge of reading references suggested for every lesson and preparing a seminar presentation. 
Learning outcomes
  1. To know how to prepare and present scientific data
  2. To know the basic principal feautures of the immune system
  3. To know the mechanisms of the immune system
  4. To understand the fundamental properties of the molecules that play a role in the immune system
  5. To learn the development and the homing sites of the cells of the immune system
  6. To understand the different types, basic principles and mechanisms of the immune responses
  7. To learn how to ask original questions about an immunological phenomenon
Course ContentTissues and cells of immune system, naive immunity, T cell ontogenesis and activation, B cell ontogenesis and activation, antigen, antigen processing and presentation, histocompatibility antigens, activation and regulation of complement system, functional and structural properties of immunoglobulins. 
References1. Basic Immunology: Functions and Disorders of the Immune System, Abul K. Abbas, Andrew H., Md. Lichtman
2. Cellular and Molecular Immunology, Abul K. Abbas, Andrew H. Lichtman, Jordan S. Pober
3. Immunobiology, Charles Janeway, Mark Walport, Paul Travers
4. Immunology, Ivan M. Roitt, Jonathan Brostoff, David K. Male
5. Medical Immunology, Tristram G. Parslow, Daniel P. Stites, Abba I. Terr, John B. Imboden
6. Nature Reviews Immunology and Nature Reviews Cancer series 

Course outline weekly

WeeksTopics
Week 1Introduction to Immunology
Week 2Tissues and Cells of Immune System
Week 3Innate immunity
Week 4Innate Lymphoid Cells
Week 5HLA-MHC System
Week 6Antigen Presentation
Week 7T cells Ontogenesis and Activation
Week 8Subsets of T Cells
Week 9 B Cell Ontogenesis and Activation
Week 10Antibody and Immune Response
Week 11Immune Memory
Week 12Terminations of Immune Response
Week 13Antigen and Inflammatory Responses
Week 14Immune Metabolism
Week 15General Exam Preparation
Week 16Final Exam

Assesment methods

Course activitiesNumberPercentage
Attendance1410
Laboratory00
Application00
Field activities00
Specific practical training00
Assignments00
Presentation120
Project00
Seminar00
Midterms00
Final exam170
Total100
Percentage of semester activities contributing grade succes1530
Percentage of final exam contributing grade succes170
Total100

WORKLOAD AND ECTS CALCULATION

Activities Number Duration (hour) Total Work Load
Course Duration (x14) 14 3 42
Laboratory 0 0 0
Application000
Specific practical training000
Field activities000
Study Hours Out of Class (Preliminary work, reinforcement, ect)1011110
Presentation / Seminar Preparation12828
Project000
Homework assignment000
Midterms (Study duration)000
Final Exam (Study duration) 13030
Total Workload2672210

Matrix Of The Course Learning Outcomes Versus Program Outcomes

D.9. Key Learning OutcomesContrubition level*
12345
1. At the end of this program, each student is expected to comprehend the innate and adaptive immune functions as well as the basic immunologic principles.     X
2. At the end of this program, each student is expected to comprehend the diseases that develop with the contribution of the immune system or the diseases that result from the impairment of immune mechanisms.    X
3. At the end of this program, each student is expected to learn the classification, nomenclature and mechanisms of immunologic disorders as well as the basic properties of immunopathology.     X
4. At the end of this program, each student is expected to comprehend the basic and differential properties as well as the development mechanisms of immunological disorders seen in various systems.     X
5. At the end of this program, each student is expected to learn how to follow the novel improvements and advances in immunology.     X
6. At the end of this program, each student is expected to learn to be able to ask original questions related to immunology as well as to choose and apply the appropriate methods and techniques in order to find an answer to the relevant questions.    X
7. At the end of this program, each student is expected to successfully and correctly perform basic immunological and molecular techniques.   X 
8. At the end of this program, each student is expected to gain the necessary skills and competence in the preparation of scientific reports, abstracts and presentations as well as to write scientific articles in peer-reviewed journals.  X  
9. At the end of this program, each student is expected to sensitively and completely accord with the ethical issues related to the field as well as to be able to work and take responsibilities as a member of the team. X   
10. At the end of this program, each student is expected to complete a research study during his/her training in the program, to learn the adequate literature knowledge about his/her study topic, to write his/her dissertation for master?s degree, to compare and to discuss the relevant information in the literature with his/her own findings.  X  
11. At the end of this program, each student is expected to demonstrate a critical approach to the discussed methods in journal clubs, seminars and data presentations as well as to successfully express his/her thoughts and concerns, and to be able to support his/her ideas with the information from relevant literature.  X  
12. At the end of this program, each student is expected to know and apply the laboratory safety and accreditation rules and regulations related to immunology.  X  
13. At the end of this program, each student is expected to know, apply and follow the methods for statistical analyses and evidence-based applications at a level sufficient to read and evaluate a scientific article.X    
14. At the end of this program, each student is expected to combine the information about his/her field of study with the information from different disciplines, to interpret this information to generate new information, to analyze and synthesize novel ideas.   X 

*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest