EFT728 - BRAIN DRUG DELIVERY SYSTEMS
| Course Name | Code | Semester | Theory (hours/week) |
Application (hours/week) |
Credit | ECTS |
|---|---|---|---|---|---|---|
| BRAIN DRUG DELIVERY SYSTEMS | EFT728 | Any Semester/Year | 3 | 0 | 3 | 9 |
| Prequisites | None | |||||
| Course language | Turkish | |||||
| Course type | Elective | |||||
| Mode of Delivery | Face-to-Face | |||||
| Learning and teaching strategies | Lecture Discussion | |||||
| Instructor (s) | Prof. Betül Arıca Yegin, Prof. Hakan Eroğlu | |||||
| Course objective | To teach the structure of barriers in central nervous system, blood brain barrier and drug delivery strategies to brain. | |||||
| Learning outcomes |
| |||||
| Course Content | Structure of barriers existing in central nervous system, drug delivery strategies to brain and imaging techniques of drug delivery systems in central nervous system | |||||
| References | Course notes, related literature data and electronical resources | |||||
Course outline weekly
| Weeks | Topics |
|---|---|
| Week 1 | Introduction to the barriers in central nervous system |
| Week 2 | Blood brain barrier (BBB) and neurovascular structures of BBB |
| Week 3 | Strategies in drug delivery to brain |
| Week 4 | Biological strategies for overcoming BBB |
| Week 5 | Drug delivery through BBB by receptor mediated vectors |
| Week 6 | Monoclonal antibodies and their properties that are used in BBB |
| Week 7 | Midterm |
| Week 8 | BBB and drug delivery systems |
| Week 9 | Transport though BBB by endocytosis |
| Week 10 | Drug delivery through BBB by using nanoparticular delivery systems 1 |
| Week 11 | Drug delivery through BBB by using nanoparticular delivery systems 2 |
| Week 12 | Drug delivery through BBB by Trojan horse method |
| Week 13 | Imaging strategies of drug delivery systems in central nervous system 1 |
| Week 14 | Imaging strategies of drug delivery systems in central nervous system 2 |
| Week 15 | Preparation for the final exam |
| Week 16 | Final exam |
Assesment methods
| Course activities | Number | Percentage |
|---|---|---|
| Attendance | 0 | 0 |
| Laboratory | 0 | 0 |
| Application | 0 | 0 |
| Field activities | 0 | 0 |
| Specific practical training | 0 | 0 |
| Assignments | 0 | 0 |
| Presentation | 0 | 0 |
| Project | 0 | 0 |
| Seminar | 0 | 0 |
| Midterms | 1 | 50 |
| Final exam | 1 | 50 |
| Total | 100 | |
| Percentage of semester activities contributing grade succes | 1 | 50 |
| Percentage of final exam contributing grade succes | 1 | 50 |
| Total | 100 | |
WORKLOAD AND ECTS CALCULATION
| Activities | Number | Duration (hour) | Total Work Load |
|---|---|---|---|
| Course Duration (x14) | 14 | 3 | 42 |
| Laboratory | 0 | 0 | 0 |
| Application | 0 | 0 | 0 |
| Specific practical training | 0 | 0 | 0 |
| Field activities | 0 | 0 | 0 |
| Study Hours Out of Class (Preliminary work, reinforcement, ect) | 14 | 4 | 56 |
| Presentation / Seminar Preparation | 0 | 0 | 0 |
| Project | 0 | 0 | 0 |
| Homework assignment | 0 | 0 | 0 |
| Midterms (Study duration) | 1 | 82 | 82 |
| Final Exam (Study duration) | 1 | 90 | 90 |
| Total Workload | 30 | 179 | 270 |
Matrix Of The Course Learning Outcomes Versus Program Outcomes
| D.9. Key Learning Outcomes | Contrubition level* | ||||
|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | |
*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest