BÄ°K603 - BASIC BIOCHEMISTRY:STRUCTURE and CATALYSIS

Course Name Code Semester Theory
(hours/week)
Application
(hours/week)
Credit ECTS
BASIC BIOCHEMISTRY:STRUCTURE and CATALYSIS BÄ°K603 1st Semester 4 0 4 7
PrequisitesStudents who have been accepted to biochemistry master's and doctoral programs and have not taken this course before/have failed can take the course. Applications other than these conditions are evaluated by the instructor.
Course languageTurkish
Course typeMust 
Mode of DeliveryFace-to-Face 
Learning and teaching strategiesLecture
Discussion
 
Instructor (s)Prof.Dr.Aslı Pınar, Assoc.Prof.Dr.Gülnihal Kulaksız Erkmen 
Course objectiveTo review the general properties of the biological macromolecules, basic cellular functions and their regulations. By the end of the course, students will gain a general idea about the basic cellular functions of the body. 
Learning outcomes
  1. Determines the biochemical features of cell and cell components.
  2. Understand the general features of carbonhydrates, classify and examines the examples.
  3. Understand the general features of lipids, classify and examines the examples.
  4. Understand the general features, structures and biochemical reactions of amino acids.
  5. Learns the basic principles about protein sturucture, general features, classification.
  6. Learns the basic features about bioenergetics, understands the formules and solve problems.
  7. Learns the basic information about enzymes, specifications, sturucture and classification.
  8. Understands the basic principles and formules about enzyme kinetics. Understands the biochemical basics of enzyme inhibiton.
Course ContentThe structural and functional organization of the cell; organelles and their functions; lipids, carbohydrates, amino acids, proteins; enzymes, enzymatic catalysis, enzyme kinetics, coenzymes; structure and function of the nucleic acids; biological membranes and transport mechanisms; bioenergetics. 
ReferencesLehninger Principles of Biochemistry, 7th ed., 2017 

Course outline weekly

WeeksTopics
Week 1Introduction to Biochemistry; Water-Buffers
Week 2Amino Acids, Peptides, and Proteins
Week 3Three-dimensional structure of proteins, Protein Function
Week 4Bioenergetics and biochemical reaction types
Week 5Enzymes
Week 6Enzymes; Carbohydrates and glycobiology
Week 7Carbohydrates and glycobiology; Preparation for midterm exam-Discussion
Week 8Preparation for midterm exam-Discussion, MIDTERM EXAM
Week 9Lipids, biological membranes and transport
Week 10Lipids, biological membranes and transport; Signal transduction
Week 11Signal transduction; Nucleotides and nucleic acids
Week 12Genes and chromosomes
Week 13Replication, recombination and repair
Week 14DNA based information technologies, Introduction to biochemistry
Week 15Preparation for final exam
Week 16FINAL EXAM

Assesment methods

Course activitiesNumberPercentage
Attendance00
Laboratory00
Application00
Field activities00
Specific practical training00
Assignments00
Presentation00
Project00
Seminar00
Midterms150
Final exam150
Total100
Percentage of semester activities contributing grade succes150
Percentage of final exam contributing grade succes150
Total100

WORKLOAD AND ECTS CALCULATION

Activities Number Duration (hour) Total Work Load
Course Duration (x14) 14 4 56
Laboratory 0 0 0
Application000
Specific practical training000
Field activities000
Study Hours Out of Class (Preliminary work, reinforcement, ect)148112
Presentation / Seminar Preparation000
Project000
Homework assignment000
Midterms (Study duration)12020
Final Exam (Study duration) 12222
Total Workload3054210

Matrix Of The Course Learning Outcomes Versus Program Outcomes

D.9. Key Learning OutcomesContrubition level*
12345
1. The student has detailed knowledge on biomolecules and metabolism; and applies and enhances this knowledge.   X 
2. The student knows and uses the equipment and instruments specific to the field of biochemistry.X    
3. The student has fundamental laboratory knowledge such as laboratory safety and basic biochemical methods, and uses this information.X    
4. Knows basic statistical methods, applies this knowledge to study and interprets the results.  X  
5. Knows professional ethics (intellectual property, academic integrity, ethics in human relations: avoids discrimination, values merit, respects privacy etc), research and publication ethics and applies this information.X    
6. Can access printed and electronic databases in the field and has the capacity to follow up recent advances in biochemistry and related fields.  X  
7. Comprehends the interaction of biochemistry with other disciplines and makes use of them.     X
8. By means of theoretical knowledge and critical reasoning, plans the related experiments and puts into practice the relevant experimental approaches to his/her special field of study.  X  
9. Evaluates the results of the study, interprets the data and writes its report.   X  
10. Independently or with the help of an advisor can define a scientific or technical problem, propose a solution and if needed solves the problem. X   
11. Takes responsibility in collaborative studies, contributes to the studies and works in harmony.X    
12. Makes a presentation on a recent topic in the field of biochemistry.X    
13. Presents or publishes his/her studies in a scientific meeting or a journal.X    
14. Reads, comprehends, interprets and criticizes an article in the field of biochemistry.  X  
15. Has proficiency in English required to follow the advances in biochemistry.X    

*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest