AMÄ°604 - GENETIC and EPIDEMIOLOGICAL STUDIES ON ALLERGIC DI
| Course Name | Code | Semester | Theory (hours/week) |
Application (hours/week) |
Credit | ECTS |
|---|---|---|---|---|---|---|
| GENETIC and EPIDEMIOLOGICAL STUDIES ON ALLERGIC DI | AMÄ°604 | 2nd Semester | 2 | 0 | 2 | 5 |
| Prequisites | None | |||||
| Course language | Turkish | |||||
| Course type | Must | |||||
| Mode of Delivery | Face-to-Face | |||||
| Learning and teaching strategies | Lecture Discussion Question and Answer | |||||
| Instructor (s) | Bülent ŞEKEREL, Özge U.SOYER, U. Murat ŞAHİNER, Esra BİRBEN, Betül BÜYÜKTİRYAKİ, Çağatay KARAASLAN | |||||
| Course objective | The purpose of this course is to teach the students about epidemiology of allergic diseases, determination of risk factors in establishment of disease and role of genetic background in development of disease, gene-environment interactions and design and application of genetic studies . | |||||
| Learning outcomes |
| |||||
| Course Content | Epidemiology of asthma, allergic rhinit and food allergies, Concepts of genetic and role in allergic diseases, Genetic studies in allergic diseases, Study design and methodology in genetic research, Gene ?environment interactions, Terminology of epigenetic and epigenetic in allergic diseases | |||||
| References | Middleton's Allergy Principlesand Practice, Eight Editions, Editors: Adkinson NF, Bochner BS, Burks W Busse WW, Holgate ST et al, 2014 Elsevier Inc., ISBN 978-0-323-08593-9 - Literature concerning related topics, to be provided to the students | |||||
Course outline weekly
| Weeks | Topics |
|---|---|
| Week 1 | Epidemiology of asthma (Bülent ŞEKEREL) |
| Week 2 | Epidemiology of allergic rhinitis (Ãœmit ÅžAHÄ°NER) |
| Week 3 | Epidemiology of food allergy (Betül BÜYÜKTİRYAKİ) |
| Week 4 | Genetics in allergic diseases (Esra BÄ°RBEN) |
| Week 5 | Candidate genestudies in allergic diseases (Esra BÄ°RBEN) |
| Week 6 | GWAS in allergic diseases (Esra BÄ°RBEN) |
| Week 7 | Metaanalysis in allergic diseases (Esra BÄ°RBEN) |
| Week 8 | Midterm exam |
| Week 9 | Gene-environment interactions in allergic diseases (Esra BÄ°RBEN) |
| Week 10 | Epigenetic concepts (Çağatay KARAASLAN) |
| Week 11 | Methods in epidemiologic research I (Çağatay KARAASLAN) |
| Week 12 | Methods in epidemiologic research II (Çağatay KARAASLAN) |
| Week 13 | miRNA in allergic diseases (Ãœmit ÅžAHÄ°NER) |
| Week 14 | Microbiota in allergic diseases (Özge SOYER) |
| Week 15 | Final Exam |
Assesment methods
| Course activities | Number | Percentage |
|---|---|---|
| Attendance | 14 | 10 |
| Laboratory | 0 | 0 |
| Application | 0 | 0 |
| Field activities | 0 | 0 |
| Specific practical training | 0 | 0 |
| Assignments | 0 | 0 |
| Presentation | 2 | 20 |
| Project | 0 | 0 |
| Seminar | 0 | 0 |
| Midterms | 1 | 20 |
| Final exam | 1 | 50 |
| Total | 100 | |
| Percentage of semester activities contributing grade succes | 17 | 50 |
| Percentage of final exam contributing grade succes | 1 | 50 |
| Total | 100 | |
WORKLOAD AND ECTS CALCULATION
| Activities | Number | Duration (hour) | Total Work Load |
|---|---|---|---|
| Course Duration (x14) | 14 | 2 | 28 |
| Laboratory | 0 | 0 | 0 |
| Application | 0 | 0 | 0 |
| Specific practical training | 0 | 0 | 0 |
| Field activities | 0 | 0 | 0 |
| Study Hours Out of Class (Preliminary work, reinforcement, ect) | 14 | 3 | 42 |
| Presentation / Seminar Preparation | 2 | 10 | 20 |
| Project | 0 | 0 | 0 |
| Homework assignment | 0 | 0 | 0 |
| Midterms (Study duration) | 1 | 20 | 20 |
| Final Exam (Study duration) | 1 | 40 | 40 |
| Total Workload | 32 | 75 | 150 |
Matrix Of The Course Learning Outcomes Versus Program Outcomes
| D.9. Key Learning Outcomes | Contrubition level* | ||||
|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | |
| 1. To gain knowledge about general features, development and pathogenesis of allergic diseases. | X | ||||
| 2. To conceive the interaction between innate and adaptive immunities in allergic inflammation and to evaluate their contribution to disease pathogenesis. | |||||
| 3. To learn cell types and their characteristics and roles in allergic diseases. | |||||
| 4. To have information concerning genetic basis of allergic diseases and gen-enviroment interactions. | X | ||||
| 5. To obtain knowledge on the legal regulations and ethical approaches directed towards clinical studies, and to comply with these ethical principles, being aware of their importance at an individual level and for society | X | ||||
| 6. To follow new developments and Technologies in the field of allergic inflammation, to know the equipment and material used in this field and to be able to use basic molecular and cell biology techniques. | X | ||||
| 7. To be able to use information technology effectively in life for professional use. | X | ||||
| 8. To discuss at a national and international level, topics related to allergic diseases, to possess the knowledge and the capability to solve problems and to master a foreign language, in such a way that this knowledge will serve as principles of life long learning. | X | ||||
| 9. To present individually or as a team opinions in a scientific environment on theoretical and practical topics, to discuss systematically with specialists, to defend and question norms, to assess the results in the framework of quality processing. | X | ||||
| 10. To analyse research data obtained in allergic diseases using statistic methods, to report according to evidence or present in a national/international scientific field. | X | ||||
| 11. To know the working standards of an allergic research laboratory, to implement the rules of data acquisition and scientific reporting, ethics and biosafety. | X | ||||
*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest