ERU607 - INTRODUCTION of RADIOPHARMACY
| Course Name | Code | Semester | Theory (hours/week) |
Application (hours/week) |
Credit | ECTS |
|---|---|---|---|---|---|---|
| INTRODUCTION of RADIOPHARMACY | ERU607 | Fall | 2 | 0 | 2 | 5 |
| Prequisites | ||||||
| Course language | Turkish | |||||
| Course type | Elective | |||||
| Mode of Delivery | Face-to-Face | |||||
| Learning and teaching strategies | Lecture Preparing and/or Presenting Reports | |||||
| Instructor (s) | Prof.Dr. Suna Erdoğan, Dr. Mine Silindir Günay | |||||
| Course objective | The aim of the course is to introduce students to the field of radiopharmacy, to give information about radiopharmaceuticals and their properties, to teach radioisotope and radiopharmaceutical production methods and radiopharmaceuticals used in clinic. | |||||
| Learning outcomes |
| |||||
| Course Content | - What is radiopharmacy? Who is a radiopharmaceutical? Radiopharmaceutical and radiochemical definition - The importance of radiopharmacy in the field of health and related terminology - Atomic structure, radioactivity, radioisotope, irradiation types - Classification of radiopharmaceuticals, half-lives, ideal radiopharmaceutical properties - Acquisition of radioactive materials, reactors, cyclotrons and generators - Radiation protection and dosimeters - Radiation and biological effects - Quality control of radiopharmaceuticals - Radiopharmaceutical laboratory design and GRP rules - Waste management - Examples from pharmacopoeias - Radiopharmaceuticals which are medicines and medical devices | |||||
| References | 1- CB Sampson, Textbook of Radiopharmacy: Theory and practice, 1994. 2- Gopal B. Saha, Fundamentals of Nuclear Pharmacy, New York, Springer, 2004. 3- PA Schubger, G Westera, Progress in Radiopharmacy, 1992. | |||||
Course outline weekly
| Weeks | Topics |
|---|---|
| Week 1 | What is radiopharmacy? Who is a radiopharmaceutical? Definition of Radiopharmaceuticals, Difference of Drugs Used in Radiology and Nuclear Medicine |
| Week 2 | The importance of radiopharmacy in health and related terminology |
| Week 3 | Atomic structure, radioactivity, radioisotope, irradiation types |
| Week 4 | Classification of radiopharmaceuticals, half-lives, ideal radiopharmaceutical properties |
| Week 5 | Preparation of radioactive materials, reactors, cyclotrons and generators |
| Week 6 | Midterm Exam |
| Week 7 | Protection from radiation and dosimeters |
| Week 8 | Radiation and biological effects |
| Week 9 | Quality control of radiopharmaceuticals |
| Week 10 | Radiopharmacy laboratory design and GRP rules |
| Week 11 | Radiopharmacy laboratory design and GRP rules |
| Week 12 | Waste management |
| Week 13 | Examples from pharmacopoeias |
| Week 14 | Radiopharmaceuticals that are medicines and medical devices |
| Week 15 | Assignment and presentation |
| Week 16 | Final Exam |
Assesment methods
| Course activities | Number | Percentage |
|---|---|---|
| Attendance | 0 | 0 |
| Laboratory | 0 | 0 |
| Application | 0 | 0 |
| Field activities | 0 | 0 |
| Specific practical training | 0 | 0 |
| Assignments | 1 | 15 |
| Presentation | 1 | 10 |
| Project | 0 | 0 |
| Seminar | 0 | 0 |
| Midterms | 1 | 25 |
| Final exam | 1 | 50 |
| Total | 100 | |
| Percentage of semester activities contributing grade succes | 3 | 50 |
| Percentage of final exam contributing grade succes | 1 | 50 |
| Total | 100 | |
WORKLOAD AND ECTS CALCULATION
| Activities | Number | Duration (hour) | Total Work Load |
|---|---|---|---|
| Course Duration (x14) | 14 | 2 | 28 |
| Laboratory | 0 | 0 | 0 |
| Application | 0 | 0 | 0 |
| Specific practical training | 0 | 0 | 0 |
| Field activities | 0 | 0 | 0 |
| Study Hours Out of Class (Preliminary work, reinforcement, ect) | 14 | 2 | 28 |
| Presentation / Seminar Preparation | 1 | 4 | 4 |
| Project | 0 | 0 | 0 |
| Homework assignment | 1 | 20 | 20 |
| Midterms (Study duration) | 1 | 30 | 30 |
| Final Exam (Study duration) | 1 | 40 | 40 |
| Total Workload | 32 | 98 | 150 |
Matrix Of The Course Learning Outcomes Versus Program Outcomes
| D.9. Key Learning Outcomes | Contrubition level* | ||||
|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | |
| 1. Has basic theoretical concepts and related approaches to provide quality in control systems used in analytical data and method validations | |||||
| 2. Has capability to decide conformity tests and to evaluate results by arranging different conditions, planning the activities for method validation and quality control | X | ||||
| 3. Has able to evaluate statistical data used for licensing medicinal products | |||||
| 4. Has knowledge on the definition of drug, formulations, properties, production and quality controls | X | ||||
| 5. Has knowledge on pharmaceutical technology in evaluating and/or preparing application dossier of licensing medicines | |||||
| 6. Has pharmacological and toxicological knowledge for licensing medicinal products | |||||
| 7. Has satisfied knowledge on safely usage of medicines. | X | ||||
| 8. Has basic and technical knowledge about radiopharmaceutics; preparing, evaluating and resulting ability for applied license dossier of radiopharmaceuticals. | |||||
| 9. Capable to perform researches on different subjects; can follow published scientific studies; can plan and end a research; able to write a report with the data. | X | ||||
| 10. Has a general idea on pharmaceutical biotechnology. | |||||
| 11. Has basic and important pharmacological and toxicological knowledge on biological products. | |||||
| 12. Has a general knowledge in registration of natural medicines, medicine out products, cosmetics, and food supplements. | |||||
| 13. Capable to discuss and/or defend pharmacoeconomic data in medicine licensing. | |||||
| 14. Has basic and technical knowledge about radiopharmacy and has foreknowledge required for prepartio of license dossier of radiopharmaceuticals about radiopharmacy. | X | ||||
*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest