MET702 - LABORATUARY STUDIES IN METABOLIC DISEASES I
| Course Name | Code | Semester | Theory (hours/week) |
Application (hours/week) |
Credit | ECTS |
|---|---|---|---|---|---|---|
| LABORATUARY STUDIES IN METABOLIC DISEASES I | MET702 | 3rd Semester | 2 | 2 | 3 | 8 |
| Prequisites | None | |||||
| Course language | Turkish | |||||
| Course type | Must | |||||
| Mode of Delivery | Face-to-Face | |||||
| Learning and teaching strategies | Lecture Discussion Question and Answer Observation Team/Group Work Preparing and/or Presenting Reports Experiment Problem Solving Project Design/Management | |||||
| Instructor (s) | Prof..Dr. R. Köksal Özgül, Dr.Öğr.Üyesi Didem Yücel Yılmaz | |||||
| Course objective | Aims to give knowledge about the laboratory applications in inherited metabolic disorders , to teach basic principles of biochemical and molecular genetics methodologies that are widely used in the laboratory | |||||
| Learning outcomes |
| |||||
| Course Content | I. Laboratory applications that are being used in the diagnosis of metabolic diseases II. Evaluation of cases with metabolic diseases III. Laboratory experiments on the bench | |||||
| References | 1.Blau N, Duran M, Gibson K.M. Laboratory Guide to the methods in biochemical genetics | |||||
Course outline weekly
| Weeks | Topics |
|---|---|
| Week 1 | Metabolic diseases |
| Week 2 | Metabolism and laboratory |
| Week 3 | General principles for obtaining biological samples, cryopreservation, biobanking |
| Week 4 | Taking patient biological samplesi, archiving, storage and transfer of the samples |
| Week 5 | Midterm exam |
| Week 6 | Laboratory study in Analytical Chemistry Lab |
| Week 7 | Laboratory study in Analytical Chemistry Lab |
| Week 8 | Laboratory study in Analytical Chemistry Lab |
| Week 9 | Laboratory study in Analytical Chemistry Lab |
| Week 10 | Midterm exam |
| Week 11 | Laboratory study in Analytical Chemistry Lab |
| Week 12 | Laboratory study in Analytical Chemistry Lab |
| Week 13 | Evaluation and data analysis obtained from laboratory studies, evaluation of test results |
| Week 14 | Evaluation and data analysis obtained from laboratory studies, |
Assesment methods
| Course activities | Number | Percentage |
|---|---|---|
| Attendance | 0 | 0 |
| Laboratory | 16 | 50 |
| Application | 0 | 0 |
| Field activities | 0 | 0 |
| Specific practical training | 0 | 0 |
| Assignments | 0 | 0 |
| Presentation | 0 | 0 |
| Project | 0 | 0 |
| Seminar | 0 | 0 |
| Midterms | 2 | 20 |
| Final exam | 1 | 30 |
| Total | 100 | |
| Percentage of semester activities contributing grade succes | 18 | 70 |
| Percentage of final exam contributing grade succes | 1 | 30 |
| Total | 100 | |
WORKLOAD AND ECTS CALCULATION
| Activities | Number | Duration (hour) | Total Work Load |
|---|---|---|---|
| Course Duration (x14) | 14 | 3 | 42 |
| Laboratory | 14 | 6 | 84 |
| Application | 0 | 0 | 0 |
| Specific practical training | 0 | 0 | 0 |
| Field activities | 0 | 0 | 0 |
| Study Hours Out of Class (Preliminary work, reinforcement, ect) | 14 | 3 | 42 |
| Presentation / Seminar Preparation | 0 | 0 | 0 |
| Project | 0 | 0 | 0 |
| Homework assignment | 0 | 0 | 0 |
| Midterms (Study duration) | 2 | 10 | 20 |
| Final Exam (Study duration) | 1 | 20 | 20 |
| Total Workload | 45 | 42 | 208 |
Matrix Of The Course Learning Outcomes Versus Program Outcomes
| D.9. Key Learning Outcomes | Contrubition level* | ||||
|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | |
| 1. Doctorate candidates are trained as a scientist and educated and experienced with the knowledge on inherited metabolic diseases, they will be able to perform advanced analytical chemistry and molecular genetics methods. | X | ||||
| 2. Doctorate candidates will be qualified at the end of the program as a result of applying laboratory experiments and studies during their thesis studies, earning theoretical knowledge from lectures , and they can continue their research activities as an independent researcher. | X | ||||
| 3. They are informed with good laboratory practices and the biosafety rules and they obey these rules for their laboratory studies. They will be knowledged for iterpretation of the primary and advanced metabolic and molecular genetics tests and experiments for thediagnosis of inherited metabolic diseases | X | ||||
| 4. They can develop new technologies which can be used for identification of metabolic diseases at the national level. They can work for development of new methods for metabolic screening programs. | X | ||||
| 5. They can criticise their own knowledge as a qualified scientist who are able to plans original research and applies it, they can apply and obey ethical rules in their studies working with a team or alone. | X | ||||
| 6. Multidiciplinary approach are needed for Metabolism research. This study area is known as biochemical genetics and requires to apply many different research activities together in the field of molecular genetics, anlytical chemistry, biochemistry, genetics, molecular cell biology. At the end of the program, trainees will be qualified on basic principles of these fields and experienced with the application of different laboratory methodologies. | X | ||||
| 7. Graduate students works in an atmosphere which is designed for interdiciplinary team research. | X | ||||
| 8. They can follow up recent advances in the field of molecular metabolism and literature at international level. | X | ||||
*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest