NNT748 - NANOTOXICOLOGY I
| Course Name | Code | Semester | Theory (hours/week) |
Application (hours/week) |
Credit | ECTS |
|---|---|---|---|---|---|---|
| NANOTOXICOLOGY I | NNT748 | Any Semester/Year | 3 | 0 | 3 | 9 |
| Prequisites | None | |||||
| Course language | Turkish | |||||
| Course type | Elective | |||||
| Mode of Delivery | Face-to-Face | |||||
| Learning and teaching strategies | Lecture Discussion | |||||
| Instructor (s) | Prof. Dr. Ülfet Pınar Erkekoğlu | |||||
| Course objective | This course aims to gain experience in searching and evaluation of possible toxic effects and mechanisms of nanoparticules/nanomaterials and the effects on human and environmental health | |||||
| Learning outcomes |
| |||||
| Course Content | Evaluation of possible toxic effects of nanoparticules/nanomaterials considering to exposure route and target tissue; investigation of toxic effect mechanisms; assessment of effects on human and environmental health | |||||
| References | 1. Fan, Chang. ?Toxicology and Risk Assessment, Principles, Methods and Applications? Marcel Dekker, 1996 2. Klaassen CD. ?The Basic Science of Poisons. Casarett & Doull?s Toxicology? Sixth Ed., McGraw-Hill Companies, 2001, New York 3. Curtis J., Greenberg, M., Kester, J., Phillips, S., Krieger, G., Nanotechonogy and nanotoxicology, Toxicological Review, 25, 245-260 (2006). 4. Holden PA et al, Ecological Nanotoxicology: Integrating Nanomaterial Hazard Considerations Across the Subcellular, Population, Community, and Ecosystems Levels, Accounts of Chemical Research, 2012, DOI: 10.1021/ar300069t | |||||
Course outline weekly
| Weeks | Topics |
|---|---|
| Week 1 | Introduction to nanotoxicology and basic principles- I |
| Week 2 | Classification of substances at nanolevel (designed and undersigned nanoparticules) |
| Week 3 | Possible toxic effects of nanoparticles/nanomaterials |
| Week 4 | Possible mechanisms of toxic effects of nanoparticles/ nanomaterials |
| Week 5 | Toxic effects of nanoparticles/ nanomaterials following exposure by inhalation |
| Week 6 | Toxic effects of nanoparticles/ nanomaterials following dermal exposure |
| Week 7 | Toxic effects of nanoparticles/ nanomaterials following oral exposure |
| Week 8 | Toxic effects related to particokinetic properties of nanoparticles/ nanomaterials |
| Week 9 | Toxic effects of nanoparticles/ nanomaterials due to their chemical structures |
| Week 10 | Antigenic effects of carbon materials |
| Week 11 | Genotoxic effects of nanoparticles/ nanomaterials |
| Week 12 | Developmental toxic effects of nanoparticles/ nanomaterials |
| Week 13 | Toxic effects of nanoparticles/ nanomaterials on environment- I |
| Week 14 | Toxic effects of nanoparticles/ nanomaterials on environment- II |
| Week 15 | Final Exam |
Assesment methods
| Course activities | Number | Percentage |
|---|---|---|
| Attendance | 0 | 0 |
| Laboratory | 0 | 0 |
| Application | 0 | 0 |
| Field activities | 0 | 0 |
| Specific practical training | 0 | 0 |
| Assignments | 2 | 30 |
| Presentation | 0 | 0 |
| Project | 0 | 0 |
| Seminar | 0 | 0 |
| Midterms | 0 | 0 |
| Final exam | 1 | 70 |
| Total | 100 | |
| Percentage of semester activities contributing grade succes | 0 | 30 |
| Percentage of final exam contributing grade succes | 0 | 70 |
| Total | 100 | |
WORKLOAD AND ECTS CALCULATION
| Activities | Number | Duration (hour) | Total Work Load |
|---|---|---|---|
| Course Duration (x14) | 14 | 3 | 42 |
| Laboratory | 0 | 0 | 0 |
| Application | 0 | 0 | 0 |
| Specific practical training | 0 | 0 | 0 |
| Field activities | 0 | 0 | 0 |
| Study Hours Out of Class (Preliminary work, reinforcement, ect) | 14 | 10 | 140 |
| Presentation / Seminar Preparation | 0 | 0 | 0 |
| Project | 0 | 0 | 0 |
| Homework assignment | 2 | 24 | 48 |
| Midterms (Study duration) | 0 | 0 | 0 |
| Final Exam (Study duration) | 1 | 40 | 40 |
| Total Workload | 31 | 77 | 270 |
Matrix Of The Course Learning Outcomes Versus Program Outcomes
| D.9. Key Learning Outcomes | Contrubition level* | ||||
|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | |
| 1. Being able to use mathematics, science, and engineering information to develop new methods in the fields of nanotechnology and nanomedicine. | X | ||||
| 2. Being able to search information in Nanotechnology and Nanomedicine fields and to reach, to evaluate and to comment on this information | X | ||||
| 3. Being able to make supplements to the literature and to develop a skill for presenting their studies fluently in written and oral forms in national and international media. | X | ||||
| 4. To have a Professional ethics and social responsibility. | X | ||||
| 5. By adopting the importance of lifetime learning in principle, actively following the developments in novel technological applications with databases and other sources. | X | ||||
| 6. Being able to choose and to use techniques, devices and software with the suitable information and communication Technologies in order to solve engineering problems. | X | ||||
| 7. To communicate in oral and written forms in a foreign language at least in the C1 grade level of European Language Portfolio in the fields of nanotechnology and nanomedicine. | X | ||||
| 8. Being able to design experiments, to do experimentation, to analyze and evaluate experimental results and to prepare a report to present. | X | ||||
| 9. Being able to do within discipline and interdisciplinary teamwork | X | ||||
*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest