BÄ°K609 - INTERCELLULAR INTERACTIONS

Course Name Code Semester Theory
(hours/week)
Application
(hours/week)
Credit ECTS
INTERCELLULAR INTERACTIONS BÄ°K609 Any Semester/Year 3 0 3 7
PrequisitesNone
Course languageTurkish
Course typeElective 
Mode of DeliveryFace-to-Face 
Learning and teaching strategiesOther: Lectures with student participation  
Instructor (s)Prof.Dr.A. Kevser Özden, Prof. Dr. Gülberk Uçar 
Course objectiveTo understand the extracellular matrix, cell-cell interactions and their interactions, their roles in development and pathology. To generate a global vision on these subjects. To privide a thorough understanding on these matters by reading and presenting related research articles. 
Learning outcomes
  1. 1. Explains why the cell membrane is not the boundary
  2. 2. Explains how the cells communicate with examples
  3. 3. Gives the names of extracellular matrix components explaining their structure and function
  4. 4. Relates cell adhesion molecules with cellular functions
  5. 5. Gives examples to extracellular matrix and cell adhesion molecule related diseases
  6. 6. Reads and avaluates research articles on these topics
Course ContentExtracellular matrix components, molecules and their signalling pathways which mediate cell-cell interactions, roles of cell-cell interaction in development and clinic. 
References1. The Cell, A Molecular Approach (2009), G. Cooper. R.E. Housman, 5th edition, ASM Press, Washington DC,
2. Molecular Biology of the Cell, B. Alberts, A. Johnson, et.al., 5th edition, Garlang Publ. Inc., New York
3. Relevant research articles in current journals 

Course outline weekly

WeeksTopics
Week 1INTRODUCTION: Multicellularity and cell environment
Week 2Extracellular matrix
Week 3Fibroblasts and collagen
Week 4Proteoglycans and glycosaminoglycans
Week 5Fibronectin and laminin
Week 6PAPER PRESENTATION
Week 7Extracellular matrix and metalloproteases
Week 8Cell-cell interactions ( selectins and Ig superfamily)
Week 9Integrins
Week 10Tight and gap junctions
Week 11PAPER PRESENTATION
Week 12Synapses
Week 13The role of intercellular interactions in signal trunsduction, differentiation and development
Week 14Clinical importance of intercellular interactions
Week 15Preparation fort he exam
Week 16FINAL EXAMINATION

Assesment methods

Course activitiesNumberPercentage
Attendance1410
Laboratory00
Application00
Field activities00
Specific practical training00
Assignments00
Presentation00
Project00
Seminar240
Midterms00
Final exam150
Total100
Percentage of semester activities contributing grade succes1650
Percentage of final exam contributing grade succes150
Total100

WORKLOAD AND ECTS CALCULATION

Activities Number Duration (hour) Total Work Load
Course Duration (x14) 14 3 42
Laboratory 0 0 0
Application000
Specific practical training000
Field activities000
Study Hours Out of Class (Preliminary work, reinforcement, ect)10220
Presentation / Seminar Preparation22448
Project000
Homework assignment8972
Midterms (Study duration)000
Final Exam (Study duration) 12828
Total Workload3566210

Matrix Of The Course Learning Outcomes Versus Program Outcomes

D.9. Key Learning OutcomesContrubition level*
12345
1. Students will be able to follow the conceptual and scientific developments related to basic measurement and evaluation techniques specific to the Exercise and Sports Physiology, and use the deep and systematic knowledge specific to the field of Exercise and Sports Physiology in their professional and academic studies.  X  
2. Has the laboratory safety and technical knowledge and skills required for laboratory studies in Exercise and Sport Physiology, and able to solve the research problems using the tools and equipment in the field. X   
3. Has the competency to analyse and integrate the information from other disciplines, synthesize new information, make decisions and solve problems by using theoretical and applied concepts and principles in Exercise and Sport Physiology with a critical approach. X   
4. Has the competency to conduct research, take part in research projects, chose the appropriate statistical methods, interpret the results of his/her work, write the report and present it in scientific meetings or publish.  X  
5. Evaluates national/international strategies, politics and practices related to Exercise and Sports Physiology in line with the national values and country realities.  X  
6. Acts in compliance with legislation, professional values and ethical principles in the formation of knowledge related to Exercise and Sports Physiology, and transfers his/her professional knowledge, skills and responsibilities to team work.  X  
7. Reads and analyses the scientific papers in Exercise and Sports Physiology, conducts and carries out evidenced based research in the concerned professional field. X   
8. Knows the importance of communication with other sciences related to Exercise and Sport Physiology, uses his/her knowledge and problem solving abilities in interdisciplinary studies.   X 
9. Adopts lifelong learning principles, identifies his/her learning needs and goals, and contributes to quality improvement, vocational training and promotion programs in Exercise and Sports Physiology.   X 
10. Establishes written, verbal and visual communication with national and international scientists and defends his/her opinions on the issues in Exercise and Sports Physiology.  X  

*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest