MEB711 - ADVANCED CELL BIOLOGY
| Course Name | Code | Semester | Theory (hours/week) |
Application (hours/week) |
Credit | ECTS |
|---|---|---|---|---|---|---|
| ADVANCED CELL BIOLOGY | MEB711 | 1st Semester | 3 | 0 | 3 | 7 |
| Prequisites | Limited to a quota of 10 students | |||||
| Course language | Turkish | |||||
| Course type | Elective | |||||
| Mode of Delivery | Face-to-Face | |||||
| Learning and teaching strategies | Lecture Discussion Question and Answer Other: Article presentation | |||||
| Instructor (s) | Prof. Didem Dayangaç-Erden, Prof. Banu Peynircioğlu, Assoc. Prof. Burcu Balcı | |||||
| Course objective | The objective of this course is to provide students knowledge about signalling through cell growth and cell differantiation, cell cycle and it's regulation, types of cell death, etc. in the area of cell biology and to make them gain the ability to do research in this area. | |||||
| Learning outcomes |
| |||||
| Course Content | In this course the following content will be discussed: Mechanisms of protein degradation; ubiquitination and structure and functions of proteosomal complexes, signal transduction; the basics of signal transduction mechanisms in the process of cell growth, differantiation and signal respond, the cell cycle and regulation mechanisms; mitosis, meiosis, cell cycle regulation via cycline and cycline dependent kinases, cell death; necrosis and apoptosis. | |||||
| References | Related current literature. | |||||
Course outline weekly
| Weeks | Topics |
|---|---|
| Week 1 | Signal Transduction: The cell surface receptors and receptor activation/ Alterations in extracellular matrix and cell membrane |
| Week 2 | Paper discussion (Presentation) |
| Week 3 | The classes of cell surface receptors Tyrosine kinases, Serine/threonine kinases |
| Week 4 | The classes of cell surface receptors Tyrosine kinases, Serine/threonine kinases |
| Week 5 | G-protein coupled cell surface receptors |
| Week 6 | Paper discussion (Presentation) |
| Week 7 | Signal transduction in the cytoplasm Secondary messengers |
| Week 8 | Signal transduction in the cytoplasm Secondary messengers |
| Week 9 | Paper discussion (Presentation) |
| Week 10 | Spatial and temporal regulation in the cytoplasm Scaffold proteins, targeting |
| Week 11 | Paper discussion (Presentation) |
| Week 12 | Cell death: Apoptosis/ Necrosis |
| Week 13 | Cell Death : Autophagy |
| Week 14 | Paper discussion (Presentation) |
| Week 15 | Preparation for the final exam |
| Week 16 | Final exam |
Assesment methods
| Course activities | Number | Percentage |
|---|---|---|
| Attendance | 0 | 0 |
| Laboratory | 0 | 0 |
| Application | 0 | 0 |
| Field activities | 0 | 0 |
| Specific practical training | 0 | 0 |
| Assignments | 0 | 0 |
| Presentation | 5 | 40 |
| Project | 0 | 0 |
| Seminar | 0 | 0 |
| Midterms | 0 | 0 |
| Final exam | 1 | 60 |
| Total | 100 | |
| Percentage of semester activities contributing grade succes | 5 | 40 |
| Percentage of final exam contributing grade succes | 1 | 60 |
| Total | 100 | |
WORKLOAD AND ECTS CALCULATION
| Activities | Number | Duration (hour) | Total Work Load |
|---|---|---|---|
| Course Duration (x14) | 14 | 3 | 42 |
| Laboratory | 0 | 0 | 0 |
| Application | 0 | 0 | 0 |
| Specific practical training | 0 | 0 | 0 |
| Field activities | 0 | 0 | 0 |
| Study Hours Out of Class (Preliminary work, reinforcement, ect) | 14 | 9 | 126 |
| Presentation / Seminar Preparation | 5 | 5 | 25 |
| Project | 0 | 0 | 0 |
| Homework assignment | 0 | 0 | 0 |
| Midterms (Study duration) | 0 | 0 | 0 |
| Final Exam (Study duration) | 1 | 15 | 15 |
| Total Workload | 34 | 32 | 208 |
Matrix Of The Course Learning Outcomes Versus Program Outcomes
| D.9. Key Learning Outcomes | Contrubition level* | ||||
|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | |
| 1. Accesses medical literature on basic and clinical immunology and -related fields and evaluates them. | X | ||||
| 2. Gains the necessary theoretical knowledge for their research and formulates hypotheses. Conducts research on immune system components and molecular structures, plans the appropriate methodology. | X | ||||
| 3. Investigates gene structures from molecular literature studies, demonstrates them through sequence analysis, interprets the data, reaches conclusions, and publishes these findings. | X | ||||
| 4. Demonstrates comprehensive and systematic knowledge on basic immunology, including understanding immunological mechanisms, immune system components, and their functions, also possesses knowledge in molecular genetics and biology. | X | ||||
| 5. Utilizes current statistical approach to evaluate the obtained data. Presents research at national and international conferences and publishes findings under mentorship. | X | ||||
| 6. Analyzes published immunological findings, proposes timely and effective solutions to encountered challenges in the laboratory, or communicates with researchers for solutions. | X | ||||
| 7. Upon completion of the basic immunology master's program, the student, under the guidance of their consultant, drafts a research proposal adhering to ethical guidelines, determines the budget, provides feedback on projects authored by other researchers, participates in collaborative projects from the planning stage, offers insights, suggests changes, and presents alternative solutions. | X | ||||
*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest