MEB618 - MOLECULAR GENETICS

Course Name Code Semester Theory
(hours/week)		 Application
(hours/week)		 Credit ECTS
MOLECULAR GENETICS MEB618 2nd Semester 3 0 3 7
PrequisitesLimited to a quota of 10 students.
Course languageTurkish
Course typeElective 
Mode of DeliveryFace-to-Face 
Learning and teaching strategiesLecture
Discussion
Team/Group Work
 
Instructor (s)Prof. Serap Dökmeci 
Course objectiveStructure, function, regulation and organization of the genetic material at the molecular level 
Learning outcomes
  1. Students will remember and use the basic knowledge about the genetic material in the cell.
  2. Students will remember and explain the relationship between molecules which take part in genetic information flow.
  3. Students will use the knowledge about gene expression and regulation.
  4. Students will be aware of latest articles about molecular genetic field.
Course ContentIn this course, general properties of nucleic acids and prokaryotic/eukaryotic cell genome, genetic information flow and regulation topics will be discussed. 
References1. Alberts: Molecular Biology of The Cell 5th Edition, 2008.
2. Genomes 3, 3rd Edition by T.A. Brown, 2006.
3. Related published articles.
 

Course outline weekly

WeeksTopics
Week 1DNA: Structure and function
Week 2DNA replication
Week 3Chromatin structure
Week 4RNA structure and function
Week 5Genetic information flow: RNA synthesis
Week 6RNA processing
Week 7Presentations and group discussion
Week 8Genetic information flow: Protein synthesis
Week 9Protein modifications
Week 10Control of gene expression in prokaryotes
Week 11Control of gene expression in eukaryotes
Week 12Eukaryotic genome organization
Week 13Eukaryotic genome organization
Week 14Homework assignment
Week 15Preparation to final exam
Week 16Final exam

Assesment methods

Course activitiesNumberPercentage
Attendance00
Laboratory00
Application00
Field activities00
Specific practical training00
Assignments110
Presentation120
Project00
Seminar00
Midterms00
Final exam170
Total100
Percentage of semester activities contributing grade succes230
Percentage of final exam contributing grade succes170
Total100

WORKLOAD AND ECTS CALCULATION

Activities Number Duration (hour) Total Work Load
Course Duration (x14) 14 3 42
Laboratory 0 0 0
Application000
Specific practical training000
Field activities000
Study Hours Out of Class (Preliminary work, reinforcement, ect)149126
Presentation / Seminar Preparation11414
Project000
Homework assignment11414
Midterms (Study duration)000
Final Exam (Study duration) 11515
Total Workload3155211

Matrix Of The Course Learning Outcomes Versus Program Outcomes

D.9. Key Learning OutcomesContrubition level*
12345
1. Graduates have knowledge related to the biophysical principles underlying all processes of life at the level of cell/tissue/organ/system    X
2. Has an ability use his/her higher intellectual processes such as critical thinking, problem solving decision development during his/her education period     
3. Can take part in some research activities to contribute to the solution of a problem in the field of biophysics     
4. Awaring of the fact that biophysics is a multidisciplinary field, follows the developments in other branches of the Medical&Basic Sciences    X
5. Can use computer software and laboratory equipment to produce appropriate stimulus, acquire the biological signals under the ideal conditions, quantitatively analyse the raw data     
6. Acquired knowledge at an expertise level in statistical methods. Can choose the most suitable method for his/her research     
7. Is aware of the importance of the ethical rules and regulations and perform laboratory research as defined by the GLP, Bio-Safety principles     
8. Has the capacity of successfully preparing and presenting the report of the research work he/she takes part in, publishing at least one manuscript     
9. Follows the activities of the national&international organizations related to his/her expertise and takes part in them     
10. Shares the knowledge he/she acquired from biophysics with partners from all parts of the society; contributes to the formation of the knowledge-based society     

*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest