KBÄ°721 - BASIC IMMUNOLOGY I

Course Name Code Semester Theory
(hours/week)		 Application
(hours/week)		 Credit ECTS
BASIC IMMUNOLOGY I KBÄ°721 1st Semester 3 0 3 8
PrequisitesNone
Course languageTurkish
Course typeElective 
Mode of DeliveryFace-to-Face 
Learning and teaching strategiesLecture
Discussion
Question and Answer
Preparing and/or Presenting Reports
 
Instructor (s)Prof. Dr. GüneÅŸ EsendaÄŸlı, Doç. Dr. Hande Canpınar, Doç.Dr. Gürcan Günaydın, Doç.Dr. NeÅŸe Ãœnver, Doç.Dr. Begüm Kocatürk 
Course objectiveTo learn the principal properties and mechanisms of the immune system as well as its components. Each student is responsible for reading the suggested references for each lecture and preparing a seminar presentation. 
Learning outcomes
  1. To know how to prepare and present scientific data
  2. To know the principal components and features of the immune system and its components
  3. To understand the fundamental properties of the molecules that play a role in the immune system
  4. To learn the development and the homing sites of the cells of the immune system
  5. To understand the different types, basic principles and mechanisms of the immune responses
  6. To know the methods and applications that are commonly used in immunology
  7. To learn to ask original questions about an immunological phenomenon
Course ContentTissues and cells of immune system, naive immunity, T cell ontogenesis and activation, B cell ontogenesis and activation, antigen, antigen processing and presentation, histocompatibility antigens, activation and regulation of complement system, functional and structural properties of immunoglobulins. 
References1. Basic Immunology: Functions and Disorders of the Immune System, Abul K. Abbas, Andrew H., Md. Lichtman
2. Cellular and Molecular Immunology, Abul K. Abbas, Andrew H. Lichtman, Jordan S. Pober
3. Immunobiology, Charles Janeway, Mark Walport, Paul Travers
4. Immunology, Ivan M. Roitt, Jonathan Brostoff, David K. Male Medical Immunology, Tristram G. Parslow, Daniel P. Stites, Abba I. Terr, John B. Imboden
6. Molecular Biology of the Cell, Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter
7. Nature Reviews Immunology and Nature Reviews Cancer series 

Course outline weekly

WeeksTopics
Week 1Properties of Immune System
Week 2Tissues and Cells of Immune System
Week 3Innate immunity
Week 4Innate Lymphoid Cells
Week 5Histocompatibility Antigens
Week 6Antigen Presentation
Week 7T Cell Ontogenesis and Activation
Week 8Subsets of T Cells
Week 9 B cell ontogenesis and activation
Week 10Antibodies and Antibody Dependent Immune Responses
Week 11Immune Memory
Week 12Termination of the Immune Response
Week 13Antigens and Inflammatory responses
Week 14Immune Metabolism
Week 15General Exam Preparation
Week 16Final Exam

Assesment methods

Course activitiesNumberPercentage
Attendance1410
Laboratory00
Application00
Field activities00
Specific practical training00
Assignments00
Presentation120
Project00
Seminar00
Midterms00
Final exam170
Total100
Percentage of semester activities contributing grade succes1530
Percentage of final exam contributing grade succes170
Total100

WORKLOAD AND ECTS CALCULATION

Activities Number Duration (hour) Total Work Load
Course Duration (x14) 14 3 42
Laboratory 0 0 0
Application000
Specific practical training000
Field activities000
Study Hours Out of Class (Preliminary work, reinforcement, ect)1212144
Presentation / Seminar Preparation12424
Project000
Homework assignment000
Midterms (Study duration)000
Final Exam (Study duration) 13030
Total Workload2869240

Matrix Of The Course Learning Outcomes Versus Program Outcomes

D.9. Key Learning OutcomesContrubition level*
12345
1. Can follow current, evidence-based and innovations in the field of vaccine technology at the doctoral level and can develop new thoughts and methods in the field by using high-level mental processes    X
2. Can plan an independent and original experimental study in the field of vaccine technology, make experimental design, perform experimental studies in appropriate environments, and analyze the data obtained and present the study outputs  X  
3. Learns, uses and develops interdisciplinary interactions related to the field of Vaccine Technology    X
4. Knows the development steps of new carrier systems and adjuvants used in vaccine technology, learns the purpose of use of new technology systems by interpreting the advantages and deficiencies of the systems relative to each other   X 
5. Can plan a scientific study using research techniques and statistical methods, and interact functionally by using strategic decision-making processes in solving the problems they will encounter   X 
6. Knows the requirements of preclinical and clinical studies from vaccine production to commercialization, good laboratory practices (GLP) and good manufacturing practices (GMP) principles in vaccine production. In addition, they will have information about the legal regulations related to vaccine production and commercialization X   
7. Gains advanced knowledge about devices and tools used in vaccine technologyX    
8. Can prepare an original scientific publication from these outputs by analyzing the findings obtained at the end of the studies carried out in the laboratory  X  
9. Knows the place of vaccine technology in the international platform, follows up-to-date information in this field and catches scientific developments    X
10. Reaches scientific knowledge with a systematic approach in the field of vaccine technology, synthesizes it with a critical perspective, and can discuss and defend the information obtained with experts and uses this information for the benefit of society    X
11. Conducts scientific research and writes articles on vaccine technologies. Knows scientific project preparation processes and requirements  X  

*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest