KBÄ°601 - BASIC IMMUNOLOGY and TUMOR BIOLOGY I

Course Name Code Semester Theory
(hours/week)		 Application
(hours/week)		 Credit ECTS
BASIC IMMUNOLOGY and TUMOR BIOLOGY I KBÄ°601 1st Semester 3 0 3 7
PrequisitesNone
Course languageTurkish
Course typeMust 
Mode of DeliveryFace-to-Face 
Learning and teaching strategiesLecture
Discussion
Question and Answer
 
Instructor (s)Prof. Dr. GüneÅŸ EsendaÄŸlı, Doç. Dr. Hande Canpınar, Doç.Dr. Gürcan Günaydın, Doç.Dr. Begüm Kocatürk 
Course objectiveTo learn the principal properties and mechanisms of the immune system as well as its components. Each student is responsible for reading the suggested references for each lecture and preparing a seminar presentation. 
Learning outcomes
  1. To know how to prepare and present scientific data
  2. To know the fundamental properties of the molecules that play a role in the immune system and the principal components and features of the immune system
  3. . To learn the development and the homing sites of the cells of the immune system
  4. To understand the different types, basic principles and mechanisms of the immune responses
  5. To know the methods and applications that are commonly used in immunology
  6. To learn to ask original questions about an immunological phenomenon
Course ContentTissues and cells of immune system, naive immunity, T cell ontogenesis and activation, B cell ontogenesis and activation, antigen, antigen processing and presentation, histocompatibility antigens, activation and regulation of complement system, functional and structural properties of immunoglobulins. 
References1. Basic Immunology: Functions and Disorders of the Immune System, Abul K.
Abbas, Andrew H., Md. Lichtman
2. Cellular and Molecular Immunology, Abul K. Abbas, Andrew H. Lichtman,
Jordan S. Pober
3. Immunobiology, Charles Janeway, Mark Walport, Paul Travers
4. Immunology, Ivan M. Roitt, Jonathan Brostoff, David K. Male
5. Medical Immunology, Tristram G. Parslow, Daniel P. Stites, Abba I. Terr, John
B. Imboden
6. Molecular Biology of the Cell, Bruce Alberts, Alexander Johnson, Julian Lewis,
Martin Raff, Keith Roberts, Peter Walter
7. Nature Reviews Immunology and Nature Reviews Cancer series 

Course outline weekly

WeeksTopics
Week 1Properties of Immune System
Week 2Tissues and Cells of Immune System
Week 3Innate immunity Components and General Concepts
Week 4Innate Immunity of Lymphoid Origins
Week 5Antigen and Antigen Presentation
Week 6T Cell Ontogenesis and Activation
Week 7T Lymphocytes Subgroups
Week 8B Lymphocytes and Antibody
Week 9Antigen and Inflammatory Responses
Week 10Termination of Immune Response
Week 11Immune Memory
Week 12Immune Metabolism
Week 13Cancer Cell Biology
Week 14Cancer and Inflammation
Week 15General Exam Preparation
Week 16Final Exam

Assesment methods

Course activitiesNumberPercentage
Attendance1410
Laboratory00
Application00
Field activities00
Specific practical training00
Assignments00
Presentation120
Project00
Seminar00
Midterms00
Final exam170
Total100
Percentage of semester activities contributing grade succes1530
Percentage of final exam contributing grade succes170
Total100

WORKLOAD AND ECTS CALCULATION

Activities Number Duration (hour) Total Work Load
Course Duration (x14) 14 3 42
Laboratory 0 0 0
Application000
Specific practical training000
Field activities000
Study Hours Out of Class (Preliminary work, reinforcement, ect)1010100
Presentation / Seminar Preparation13030
Project000
Homework assignment000
Midterms (Study duration)000
Final Exam (Study duration) 13838
Total Workload2681210

Matrix Of The Course Learning Outcomes Versus Program Outcomes

D.9. Key Learning OutcomesContrubition level*
12345
1. At the end of this program, each student is expected to comprehend the basic immunological principles and methods as well as the innate and adaptive immune functions.     X
2. Each student is expected to learn the differences of cancer biology from normal cell biology, the mechanisms involved in cancer development and various immune responses generated against different types of cancers.  X  

*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest