KÄ°M718 - AFFINITY SENSORS

Course Name Code Semester Theory
(hours/week)
Application
(hours/week)
Credit ECTS
AFFINITY SENSORS KÄ°M718 Any Semester/Year 3 0 3 10
Prequisitesnone
Course languageTurkish
Course typeElective 
Mode of DeliveryFace-to-Face 
Learning and teaching strategiesLecture
Discussion
Question and Answer
 
Instructor (s)Prof. Dr. Nilay Bereli 
Course objectiveThe aim of the course is to introduce what are chemical sensors; principles and applications of affinity based biosensors and their types depending on the transducers. 
Learning outcomes
  1. At the end of the class, student have been learnt What are chemical sensors? Definition and components /Recognition methods / Transduction methods Sensor configuration and fabrication / Sensor calibration Sensors in flow analysis systems / Applications of chemical sensors
  2. Principles of affinity based biosensors
  3. Principles of affinity based biosensors
  4. Protein structure and properties
  5. Enzymes and enzymatic sensors
  6. Affinity based recognition
  7. Nucleic acids in chemical sensors
  8. Nanomaterial applications in chemical sensors
Course ContentThe course covers the topics of; learning general terms relating to chemical sensors, definiton and application of affinity based biosensors, and their types depending on the transducers. 
ReferencesLecture notes / Recent publications
F.G. Banica, "Chemical sensors and biosensors: Fundamentals and applications", 22, John Wileys & Sons Ltd., West Sussex, UK.
K.R. Rogers, A. Mulchandani,"Affinity Biosensors: Techniques and Protocols (Methods in Biotechnology)", 1998, Humana Press Inc, New Jersey, USA.
K. Iniewski, "Biological and Medical Sensor Technologies", 2012, CRC Press, Taylor & Francis Group, Florida, USA. 

Course outline weekly

WeeksTopics
Week 1First meeting and general information about course and its structure
Week 2-What are chemical sensors - Definition and components /Recognition methods / Transduction methods - Sensor configuration and fabrication / Sensor calibration - Sensors in flow analysis systems / Applications of chemical sensors
Week 3-Principles of affinity based biosensors -Protein structure and properties -Enzymes and enzymatic sensors -Affinity based recognition
Week 4-Nucleic acids in chemical sensors -Nanomaterial applications in chemical sensors
Week 5-Thermochemical sensors -Potentiometric sensors -Amperometric enzyme sensors
Week 6-Electrochemical affinity and nucleic acid sensors -Electrical impedance based sensors
Week 7-Optical sensors-fundamentals -Electromagnetic radiation / Optical waveguides -Spectrochemical transduction methods / Fiber optic sensors arrays
Week 8-Label-free transduction - Surface plasmon resonance spectrometry -Interferometric transduction
Week 9-Optical sensors-applications -Nanomaterials in optical transduction -Quantum dots / Carbon nanotubes / Metal nanoparticles
Week 10-Nanomaterials in optical transduction -Porous silicon / Luminescent lanthanide compounds
Week 11-Acoustic wave sensors -Piezoelectric effect / Quartz crystal microbalance sensors -Surface acoustic wave sensors -Microcantilever sensors
Week 12Midterm
Week 13Student presentation (hot topics in affinity sensors)
Week 14Student presentation (hot topics in affinity sensors)
Week 15General remarks
Week 16Final exam

Assesment methods

Course activitiesNumberPercentage
Attendance1330
Laboratory00
Application00
Field activities00
Specific practical training00
Assignments00
Presentation120
Project00
Seminar00
Midterms130
Final exam150
Total130
Percentage of semester activities contributing grade succes150
Percentage of final exam contributing grade succes150
Total100

WORKLOAD AND ECTS CALCULATION

Activities Number Duration (hour) Total Work Load
Course Duration (x14) 14 3 42
Laboratory 0 0 0
Application000
Specific practical training000
Field activities000
Study Hours Out of Class (Preliminary work, reinforcement, ect)1410140
Presentation / Seminar Preparation14040
Project000
Homework assignment000
Midterms (Study duration)14040
Final Exam (Study duration) 14040
Total Workload31133302

Matrix Of The Course Learning Outcomes Versus Program Outcomes

D.9. Key Learning OutcomesContrubition level*
12345
1. Specializes through postgraduate studies and introduces innovative scientific concepts to their field.    X
2. Analyzes sophisticated ideas and obtains original results by evaluating interdisciplinary interactions.   X 
3. Evaluates, criticizes, interprets, and communicates new information in their field without prejudice.   X 
4. Develops new ideas, methods, and applications in their field or adapts them to different areas.   X 
5. Develops scientific strategies using various research methods based on advanced knowledge and experience.    X
6. Contributes to scientific knowledge by publishing original articles in national/international refereed journals.  X  
7. Contributes to original work and interdisciplinary problem-solving, taking a leadership role in their field.  X  
8. Develops new thoughts and methods using creative and critical thinking for problem-solving.   X 
9. Defends original views and communicates effectively while discussing with competent people.  X  
10. Accesses international sources, updates knowledge, and communicates with colleagues using a foreign language.  X  
11. Conducts research in national and international scientific research groups.    X
12. Keeps track of advancements in their field, internalizes them, and contributes to society's knowledge and sustainability.   X 
13. Manages data related to their field effectively and securely, considering societal, scientific, cultural, and ethical values.   X 

*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest