BYL742 - REGULATION of GENE EXPRESSION
| Course Name | Code | Semester | Theory (hours/week) |
Application (hours/week) |
Credit | ECTS |
|---|---|---|---|---|---|---|
| REGULATION of GENE EXPRESSION | BYL742 | 1st Semester | 2 | 3 | 3 | 9 |
| Prequisites | ||||||
| Course language | Turkish | |||||
| Course type | Elective | |||||
| Mode of Delivery | Face-to-Face | |||||
| Learning and teaching strategies | Lecture Discussion Question and Answer Demonstration Experiment | |||||
| Instructor (s) | Assoc. Prof. Esra Birben | |||||
| Course objective | Understand to importance of the regulation of gene expression in regulating cellular metabolism and in orchestrating and maintaining the structral and functional differences during development. | |||||
| Learning outcomes |
| |||||
| Course Content | Regulation of gene expression in bacteria, regulation of gene expression in eukaryotes, the genetic control of development | |||||
| References | ||||||
Course outline weekly
| Weeks | Topics |
|---|---|
| Week 1 | Molecular mechanisms of signal transduction(T) his operon (P) |
| Week 2 | Discovery of the lac operon,negative control,catabolite repression:positive control (T) his operon (P) |
| Week 3 | Arabinose operon,trp. operon (T) his operon (P) |
| Week 4 | Bacteriophage life cycles,complex operons,Alternative sigma factors and function,regulon systems (T) his operon (P) |
| Week 5 | Gene regulation in eukaryotes,transcriptional control (T)his operon (P) |
| Week 6 | GAL system in yeast |
| Week 7 | Chromatine-remodeling (T) SOS regulon(P) |
| Week 8 | Genomic imprinting (T) SOS regulon(P) |
| Week 9 | Post-transcriptional control, miRNA?s (T) SOS regulon(P) |
| Week 10 | Translational control (T) Discussion(P) |
| Week 11 | Genetic control of development (T) |
| Week 12 | Genetic control of development |
| Week 13 | Control of cell cycle and cancer (T) Discussion (P) |
| Week 14 | Midterm |
| Week 15 | Studying for final exam |
| Week 16 | Final exam |
Assesment methods
| Course activities | Number | Percentage |
|---|---|---|
| Attendance | 0 | 0 |
| Laboratory | 1 | 30 |
| Application | 0 | 0 |
| Field activities | 0 | 0 |
| Specific practical training | 0 | 0 |
| Assignments | 0 | 0 |
| Presentation | 0 | 0 |
| Project | 0 | 0 |
| Seminar | 0 | 0 |
| Midterms | 1 | 30 |
| Final exam | 1 | 40 |
| Total | 100 | |
| Percentage of semester activities contributing grade succes | 0 | 60 |
| Percentage of final exam contributing grade succes | 0 | 40 |
| Total | 100 | |
WORKLOAD AND ECTS CALCULATION
| Activities | Number | Duration (hour) | Total Work Load |
|---|---|---|---|
| Course Duration (x14) | 14 | 2 | 28 |
| Laboratory | 14 | 3 | 42 |
| Application | 0 | 0 | 0 |
| Specific practical training | 0 | 0 | 0 |
| Field activities | 0 | 0 | 0 |
| Study Hours Out of Class (Preliminary work, reinforcement, ect) | 13 | 10 | 130 |
| Presentation / Seminar Preparation | 1 | 4 | 4 |
| Project | 0 | 0 | 0 |
| Homework assignment | 1 | 10 | 10 |
| Midterms (Study duration) | 2 | 15 | 30 |
| Final Exam (Study duration) | 1 | 20 | 20 |
| Total Workload | 46 | 64 | 264 |
Matrix Of The Course Learning Outcomes Versus Program Outcomes
| D.9. Key Learning Outcomes | Contrubition level* | ||||
|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | |
| 1. Based on master qualifications in the field he/she improves and deepens the actual and advanced information with individual thought and/or research in the level of the specialty. | X | ||||
| 2. Comprehends interdisciplinary interaction related with his/her field; performs analysis and synthesis of the new and complex ideas and reaches the original results by using expert knowledge in assessment. | X | ||||
| 3. Evaluates and uses knowledge with systematic approach in his/her field; makes critical analysis, synthesis, and assessment of knowledge and transfer it. | X | ||||
| 4. Develops a new idea, method, design and/or application for innovation in his/her field or performs a known idea, method, design and/or application to a different field. Researches comprehends, designs, adapts and implements an original subject. | X | ||||
| 5. Possesses the high level skills in using research methods in his/her field. | X | ||||
| 6. Publishes at least one article related with his/her field in national or international academic journals. | X | ||||
| 7. Works in environment, which requires solving original and interdisciplinary problems. | X | ||||
| 8. Can develop new ideas and methods related to his/her field using upper level intellectual processes such as innovative and critical thinking, solving problems and enacting. | X | ||||
| 9. Able to make a scientific research at national or international academic groups. | X | ||||
| 10. Contributes to the solution of the social, scientific, cultural and ethical problems in his/her field and supports the improvement of these values. | X | ||||
| 11. Presents the scientific and technologic progresses in his/her field, contributes the processes of being an informed society where he/she lives and supports the development of values. | X | ||||
*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest